This article explores how mules were procured in Cyprus for the Salonica campaign and how they were treated by Cypriot muleteers in the British army in Macedonia. Cyprus provides an ideal case since over 6,000 mules were recruited for the Salonica campaign, presenting a sizeable sample for analysis of recruitment strategies and practices. Equally, since over 12,000 Cypriot muleteers served in the British army in Salonica and later in Istanbul during and after the Great War (from July 1916 to April 1920), the focus on the treatment of mules by Cypriot muleteers offers a significant sample. This article contributes to the growing historiography on the role of equines and their treatment and condition in the Great War. It argues that Cypriot mules were procured in significant numbers and became important to British supply and logistics in Salonica. Cypriot muleteers treated their mules relatively well, and therefore mules in Salonica, although overworked, were generally in reasonable condition.