TY - JOUR
T1 - Flavonoids from the leaves and stems of Dodonaea polyandra: A Northern Kaanju medicinal plant
AU - Simpson, Bradley
AU - Claudie, David
AU - Smith, Nick
AU - Gerber, Jacobus
AU - McKinnon, Ross
AU - Semple, Susan
PY - 2011/10/10
Y1 - 2011/10/10
N2 - Three prenylated flavonoids 5,7,4′-trihydroxy-3′(3-methylbut-2- enyl)-3-methoxy flavone, 5,7-dihydroxy-3′(3-methylbut-2-enyl)-3,4′- dimethoxy flavone and 5,7,4′-trihydroxy-3′,5′(3-methylbuyt-2- enyl)-3-methoxy flavone together with three other known flavonoids were isolated from the medicinal plant Dodonaea polyandra. The plant is used in the traditional medicine system of Northern Kaanju people of Cape York Peninsula, Queensland, Australia. The extracts studied have previously been found to possess anti-inflammatory activity. Successive fractionation of leaf and stem extracts by column and high performance liquid chromatography led to the isolation of these compounds. Their structures were determined using a number of spectroscopic techniques including 1D and 2D NMR and high resolution mass spectroscopy. The structural elucidation is reported herein accompanied by full 1H and 13C NMR spectroscopic data. Spectroscopic data of known compounds was in agreement with that previously reported in literature.
AB - Three prenylated flavonoids 5,7,4′-trihydroxy-3′(3-methylbut-2- enyl)-3-methoxy flavone, 5,7-dihydroxy-3′(3-methylbut-2-enyl)-3,4′- dimethoxy flavone and 5,7,4′-trihydroxy-3′,5′(3-methylbuyt-2- enyl)-3-methoxy flavone together with three other known flavonoids were isolated from the medicinal plant Dodonaea polyandra. The plant is used in the traditional medicine system of Northern Kaanju people of Cape York Peninsula, Queensland, Australia. The extracts studied have previously been found to possess anti-inflammatory activity. Successive fractionation of leaf and stem extracts by column and high performance liquid chromatography led to the isolation of these compounds. Their structures were determined using a number of spectroscopic techniques including 1D and 2D NMR and high resolution mass spectroscopy. The structural elucidation is reported herein accompanied by full 1H and 13C NMR spectroscopic data. Spectroscopic data of known compounds was in agreement with that previously reported in literature.
KW - Australian indigenous medicine
KW - Dodonaea polyandra
KW - Prenylated flavonoid
KW - Sapindaceae
UR - http://www.scopus.com/inward/record.url?scp=80051548272&partnerID=8YFLogxK
U2 - 10.1016/j.phytochem.2011.05.006
DO - 10.1016/j.phytochem.2011.05.006
M3 - Article
SN - 0031-9422
VL - 72
SP - 1883
EP - 1888
JO - Phytochemistry
JF - Phytochemistry
IS - 14-15
ER -