Flavonoids from the leaves and stems of Dodonaea polyandra: A Northern Kaanju medicinal plant

Bradley Simpson, David Claudie, Nick Smith, Jacobus Gerber, Ross McKinnon, Susan Semple

    Research output: Contribution to journalArticlepeer-review

    12 Citations (Scopus)

    Abstract

    Three prenylated flavonoids 5,7,4′-trihydroxy-3′(3-methylbut-2- enyl)-3-methoxy flavone, 5,7-dihydroxy-3′(3-methylbut-2-enyl)-3,4′- dimethoxy flavone and 5,7,4′-trihydroxy-3′,5′(3-methylbuyt-2- enyl)-3-methoxy flavone together with three other known flavonoids were isolated from the medicinal plant Dodonaea polyandra. The plant is used in the traditional medicine system of Northern Kaanju people of Cape York Peninsula, Queensland, Australia. The extracts studied have previously been found to possess anti-inflammatory activity. Successive fractionation of leaf and stem extracts by column and high performance liquid chromatography led to the isolation of these compounds. Their structures were determined using a number of spectroscopic techniques including 1D and 2D NMR and high resolution mass spectroscopy. The structural elucidation is reported herein accompanied by full 1H and 13C NMR spectroscopic data. Spectroscopic data of known compounds was in agreement with that previously reported in literature.

    Original languageEnglish
    Pages (from-to)1883-1888
    Number of pages6
    JournalPhytochemistry
    Volume72
    Issue number14-15
    DOIs
    Publication statusPublished - 10 Oct 2011

    Keywords

    • Australian indigenous medicine
    • Dodonaea polyandra
    • Prenylated flavonoid
    • Sapindaceae

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