Pain evolved to alert us to and protect us from actual or potential tissue damage. There are three common forms: nociceptive pain, which is associated with the detection of damaging stimuli; inflammatory pain, associated with inflammation or infection; and chronic pain, which is a maladaptive, long-term form of pain. Writing in Nature, Aguilera-Lizarraga et al. report evidence from mice and humans indicating a previously unknown mechanism that contributes to chronic gut pain...
- Medical research