Forensic applications of desorption electrospray ionisation mass spectrometry (DESI-MS)

Marie Morelato, Alison Beavis, Kenneth Kirkbride, Claude Roux

    Research output: Contribution to journalReview articlepeer-review

    81 Citations (Scopus)

    Abstract

    Desorption electrospray ionisation mass spectrometry (DESI-MS) is an emerging analytical technique that enables in situ mass spectrometric analysis of specimens under ambient conditions. It has been successfully applied to a large range of forensically relevant materials. This review assesses and highlights forensic applications of DESI-MS including the analysis and detection of illicit drugs, explosives, chemical warfare agents, inks and documents, fingermarks, gunshot residues and drugs of abuse in urine and plasma specimens. The minimal specimen preparation required for analysis and the sensitivity of detection achieved offer great advantages, especially in the field of forensic science.

    Original languageEnglish
    Pages (from-to)10-21
    Number of pages12
    JournalForensic Science International
    Volume226
    Issue number1-3
    DOIs
    Publication statusPublished - 10 Mar 2013

    Keywords

    • Chemical warfare agents (CWAs)
    • Desorption electrospray ionisation mass spectrometry (DESI-MS)
    • Explosives
    • Gunshot residues (GSR)
    • Illicit drugs
    • Toxicology

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