Abstract
DNA profiling has greatly changed the way in which human identification is performed for the purpose of a forensic investigation. This chapter outlines the current situation regarding forensic science and diagnostic techniques. Forensic science reacts to developments in other areas of science, frequently adapting techniques developed for nonforensic purposes. One of the greatest advances in forensic science has been the introduction of DNA profiling. To date DNA profiling is performed using microsatellite amplicons (STRs) where hypervariability exists within the number of repeats of a short DNA sequence motif. Greater than 3 million samples have been analyzed by this method on the UK National DNA database alone, with currently an increasing number of samples on the US CODIS and similar DNA databases throughout Europe. In forensic toxicology the samples are normally from one person only and it may be in application such as this that SNP typing will find a role.
| Original language | English |
|---|---|
| Title of host publication | Molecular analyses |
| Editors | Scott O. Rogers |
| Place of Publication | Florida, USA |
| Publisher | CRC Press |
| Chapter | 30 |
| Pages | 297-303 |
| Number of pages | 7 |
| ISBN (Electronic) | 978-1-003-24743-2 |
| ISBN (Print) | 978-0-367-90371-8, 978-1-032-16190-7 |
| DOIs | |
| Publication status | Published - 2022 |
| Externally published | Yes |
Keywords
- Forensic Identification
- Molecular Diagnostic Technology
- DNA profiling
- Deoxyribonucleic acid
- DNA technology
- forensic science