Fractional CO 2 laser for treatment of stress urinary incontinence

Fariba Behnia-Willison, Tran T.T. Nguyen, Behrang Mohamadi, Thierry G. Vancaillie, Alan Lam, Nadia N. Willison, Jett Zivkovic, Richard J. Woodman, Monika M. Skubisz

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Objectives: To evaluate the impact of trans-vaginal fractional CO 2 laser treatment on symptoms of stress urinary incontinence (SUI) in women. Study design: Women clinically diagnosed with SUI preferring non-surgical treatment were recruited to the study. Fractional CO 2 laser system (MonaLisa T, DEKA) treatments were administered trans-vaginally every 4–6 weeks for a total of three treatments. Response to treatment was assessed at baseline (T1), at 3 months after treatment completion (T2) and at 12–24-month follow-up (T3) using the Australian Pelvic Floor Questionnaire (APFQ). The primary outcome was changes in reported symptoms of SUI. Secondary outcomes assessed included bladder function, urgency, urge urinary incontinence (UUI), pad usage, impact of urinary incontinence on quality of life (QOL) and degree of bothersome bladder. Results: Fifty-eight women were recruited and received the study treatment protocol. Eighty-two percent of participants reported an improvement in symptoms of SUI at completion of treatment (mild to no SUI) (p = <0.01). Treatment effect waned slightly when assessed at follow-up. Nevertheless, 71% of participants reported ongoing improvement in SUI symptoms at 12–24 months (p < 0.01). All secondary outcome measures were improved after treatment compared to baseline. Conclusions: This study suggests that fractional CO 2 laser is a safe, feasible, and beneficial treatment for SUI and may have a role as a minimally-invasive alternative to surgical management.

Original languageEnglish
Article number100004
Number of pages5
JournalEuropean Journal of Obstetrics and Gynecology and Reproductive Biology: X
Publication statusPublished - 11 Jan 2019

Bibliographical note

(CC BY-NC-ND 4.0) Open Access article licensed under a Creative Commons Attribution Non-Commercial license, which permits others to distribute this work non-commercially, provided the original work is properly cited and the use is non-commercial. If you remix, transform, or build upon the material, you may not distribute the modified material. See:


  • Bladder function
  • Bladder urgency
  • Fractional CO laser
  • Stress urinary incontinence
  • Urinary leakage


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