Frailty index from routine laboratory measurements correlates with leukocyte telomere length

Elsa Dent; Emiel O. Hoogendijk; Max Moldovan

doi:10.1111/ggi.13257

Frailty index from routine laboratory measurements correlates with leukocyte telomere length

Elsa Dent, Emiel O. Hoogendijk, Max Moldovan

Research output: Contribution to journal › Letter › peer-review

7 Citations (Scopus)

Abstract

Frailty is one of the most debilitating conditions affecting older adults worldwide; it heightens the risk for both disability and premature mortality, and is characterized by an increased vulnerability of physiological systems to external stressors.¹ Although human physiological systems have an in-built reserve to cope with stressors, aging reduces this physiological reserve.² Frailty is thought to manifest when multiple physiological systems fall below their coping thresholds.²

Original language	English
Pages (from-to)	654-655
Number of pages	2
Journal	Geriatrics and Gerontology International
Volume	18
Issue number	4
DOIs	https://doi.org/10.1111/ggi.13257
Publication status	Published - Apr 2018
Externally published	Yes

Keywords

Frailty
Leukocyte
Ageing
Telomeres

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10.1111/ggi.13257Licence: In Copyright

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abstract = "Frailty is one of the most debilitating conditions affecting older adults worldwide; it heightens the risk for both disability and premature mortality, and is characterized by an increased vulnerability of physiological systems to external stressors.1 Although human physiological systems have an in-built reserve to cope with stressors, aging reduces this physiological reserve.2 Frailty is thought to manifest when multiple physiological systems fall below their coping thresholds.2",

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AU - Dent, Elsa

AU - Hoogendijk, Emiel O.

AU - Moldovan, Max

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AB - Frailty is one of the most debilitating conditions affecting older adults worldwide; it heightens the risk for both disability and premature mortality, and is characterized by an increased vulnerability of physiological systems to external stressors.1 Although human physiological systems have an in-built reserve to cope with stressors, aging reduces this physiological reserve.2 Frailty is thought to manifest when multiple physiological systems fall below their coping thresholds.2

KW - Frailty

KW - Leukocyte

KW - Ageing

KW - Telomeres

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UR - http://purl.org/au-research/grants/nhmrc/1112672

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M3 - Letter

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AN - SCOPUS:85045102728

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JF - Geriatrics and Gerontology International

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ER -

Frailty index from routine laboratory measurements correlates with leukocyte telomere length

Abstract

Keywords

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