Fruit intake and abdominal aortic calcification in elderly women: a prospective cohort study

N Bondonno, Joshua Lewis, Richard Prince, W Lim, G Wong, J Schousboe, Richard Woodman, Douglas Kiel, Catherine Bondonno, natalie ward, Kevin Croft, Jonathan Hodgson

    Research output: Contribution to journalArticlepeer-review

    18 Citations (Scopus)


    Cardiovascular disease (CVD) is the leading cause of death worldwide. There is a consistent inverse relationship between fruit intake with CVD events and mortality in cross-sectional and prospective observational studies, but the relationship of fruit intake with measurements of atherosclerosis in humans is less clear. Nutritional effects on abdominal aortic calcification (AAC), a marker for subclinical intimal and medial atherosclerotic vascular disease, have not been studied previously. The aim of this study was to examine the cross-sectional relationship of total and individual fruit (apple, pear, orange and other citrus, and banana) intake with AAC, scored between 0 and 24. The current study assessed baseline data for a cohort of 1052 women over 70 years of age who completed both a food frequency questionnaire assessing fruit intake, and underwent AAC measurement using dual energy X-ray absorptiometry. AAC scores were significantly negatively correlated with total fruit and apple intakes (p < 0.05), but not with pear, orange or banana intakes (p > 0.25). In multivariable-adjusted logistic regression, each standard deviation (SD; 50 g/day) increase in apple intake was associated with a 24% lower odds of having severe AAC (AAC score >5) (odd ratio OR): 0.76 (0.62, 0.93), p = 0.009). Total and other individual fruit intake were not associated with increased odds of having severe AAC. Apple but not total or other fruit intake is independently negatively associated with AAC in older women.

    Original languageEnglish
    Article number159
    Pages (from-to)Art: 159
    Number of pages12
    Issue number3
    Publication statusPublished - 10 Mar 2016


    • Abdominal aortic calcification
    • Apples
    • Atherosclerosis
    • Cardiovascular disease
    • Fruit


    Dive into the research topics of 'Fruit intake and abdominal aortic calcification in elderly women: a prospective cohort study'. Together they form a unique fingerprint.

    Cite this