Gastrointestinal microbiota and metabolite biomarkers in children with autism spectrum disorders

L Wang, Michael Conlon, Claus Christophersen, Michael Sorich, Manya Angley

    Research output: Contribution to journalArticle

    36 Citations (Scopus)

    Abstract

    Autism spectrum disorder (ASD) is a neurodevelopmental disorder. Many affected individuals also display symptoms of gastrointestinal (GI) disturbance, suggesting GI factors may play an important role in the pathogenesis of ASD and/or related complications. The current review will focus on evidence supporting a role for the GI microbiota and their fermentation products in the etiology and/or symptoms of ASD, and their potential use as biomarkers. GI-related biomarkers could potentially enable early identification of ASD at risk of GI disturbance, and thereby guide targeted interventions, potentially improving the health and quality of life of affected individuals.

    Original languageEnglish
    Pages (from-to)331-334
    Number of pages4
    JournalBiomarkers in Medicine
    Volume8
    Issue number3
    DOIs
    Publication statusPublished - 2014

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