Gd 2O 3 nanoparticles: size-dependent nuclear magnetic resonance

A.T.M. Anishur Rahman; Peter Majewski; Krasimir Vasilev

doi:10.1002/cmmi.1481

Gd ₂O ₃ nanoparticles: size-dependent nuclear magnetic resonance

A.T.M. Anishur Rahman, Peter Majewski, Krasimir Vasilev

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

In this communication, we demonstrate that there is an optimum gadolinium oxide (Gd ₂O ₃) nanoparticle size of 2.3nm; in the presence of Gd ₂O ₃ particles smaller and larger than this critical size, the spin-lattice relaxation rate (T ₁=1/r ₁) of water protons at 7.0T drastically decreases. Since r ₁ is directly related to the quality of magnetic resonance imaging, the results presented here have significant implications for clinical diagnostics.

Original language	English
Pages (from-to)	92-95
Number of pages	4
Journal	Contrast Media and Molecular Imaging
Volume	8
Issue number	1
DOIs	https://doi.org/10.1002/cmmi.1481
Publication status	Published - Jan 2013
Externally published	Yes

Keywords

Contrast agent
Gadolinium oxide
Magnetic resonance imaging (MRI)
Nuclear magnetic resonance (NMR)

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AB - In this communication, we demonstrate that there is an optimum gadolinium oxide (Gd 2O 3) nanoparticle size of 2.3nm; in the presence of Gd 2O 3 particles smaller and larger than this critical size, the spin-lattice relaxation rate (T 1=1/r 1) of water protons at 7.0T drastically decreases. Since r 1 is directly related to the quality of magnetic resonance imaging, the results presented here have significant implications for clinical diagnostics.

KW - Contrast agent

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KW - Magnetic resonance imaging (MRI)

KW - Nuclear magnetic resonance (NMR)

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Gd ₂O ₃ nanoparticles: size-dependent nuclear magnetic resonance

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