Generalized anxiety disorder prevalence and comorbidity with depression in coronary heart disease: A meta-analysis

Phillip Tully, Suzie Cosh

    Research output: Contribution to journalArticle

    31 Citations (Scopus)

    Abstract

    Generalized anxiety disorder prevalence and comorbidity with depression in coronary heart disease patients remain unquantified. Systematic searching of Medline, Embase, SCOPUS and PsycINFO databases revealed 1025 unique citations. Aggregate generalized anxiety disorder prevalence (12 studies, N = 3485) was 10.94 per cent (95% confidence interval: 7.8-13.99) and 13.52 per cent (95% confidence interval: 8.39-18.66) employing Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria (random effects). Lifetime generalized anxiety disorder prevalence was 25.80 per cent (95% confidence interval: 20.84-30.77). In seven studies, modest correlation was evident between generalized anxiety disorder and depression, Fisher's Z =.30 (95% confidence interval:.19-.42), suggesting that each psychiatric disorder is best conceptualized as contributing unique variance to coronary heart disease prognosis.

    Original languageEnglish
    Pages (from-to)1601-1616
    Number of pages16
    JournalJournal of Health Psychology
    Volume18
    Issue number12
    DOIs
    Publication statusPublished - 2013

    Keywords

    • comorbidity
    • coronary heart disease
    • depression
    • generalized anxiety disorder
    • meta-analysis

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