Abstract
Measuring the genetic relatedness between different species is one of the major challenges in the field of phylogenetics. Genetic distance calculation based on DNA data is highly using a mechanism to determine inter species relationships. Genetic distance computation can be further bifurcated as alignment-free sequencing and alignment based sequencing. With this research we are presenting alignment free genetic distance calculation technique which is based on locality sensitive hashing(LSH). By this approach we are hashing large DNA sequences into numeric arrays and make comparison more efficient and simplified.
Original language | English |
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Publisher | bioRxiv, Cold Spring Harbor Laboratory |
Number of pages | 6 |
DOIs | |
Publication status | Submitted - 19 Jun 2020 |
Externally published | Yes |
Keywords
- phylogenetics
- genetic relatedness
- genetic distance
- locality sensitive hashing
- min-hashing