Purpose: To report a case with giant retinal tear after pneumatic retinopexy. To our knowledge, this is only the second case of a giant retinal tear after pneumatic retinopexy reported. Methods: This is a descriptive case study. Results: A 43-year-old myopic man underwent pneumatic retinopexy for right eye rhegmatogenous retinal detachment. Postoperative course was complicated by a giant retinal tear, which was treated successfully. Conclusion: Though rare, giant retinal tears can occur after pneumatic retinopexy. The likely mechanism is increased vitreous traction because of expansion of gas in a predisposed myopic eye.