Abstract
BACKGROUND: The sustainable development goals (SDGs) aim to end HIV/AIDS as a public health threat by 2030. Understanding the current state of the HIV epidemic and its change over time is essential to this effort. This study assesses the current sex-specific HIV burden in 204 countries and territories and measures progress in the control of the epidemic. METHODS: To estimate age-specific and sex-specific trends in 48 of 204 countries, we extended the Estimation and Projection Package Age-Sex Model to also implement the spectrum paediatric model. We used this model in cases where age and sex specific HIV-seroprevalence surveys and antenatal care-clinic sentinel surveillance data were available. For the remaining 156 of 204 locations, we developed a cohort-incidence bias adjustment to derive incidence as a function of cause-of-death data from vital registration systems. The incidence was input to a custom Spectrum model. To assess progress, we measured the percentage change in incident cases and deaths between 2010 and 2019 (threshold >75% decline), the ratio of incident cases to number of people living with HIV (incidence-to-prevalence ratio threshold <0·03), and the ratio of incident cases to deaths (incidence-to-mortality ratio threshold <1·0). FINDINGS: In 2019, there were 36·8 million (95% uncertainty interval [UI] 35·1-38·9) people living with HIV worldwide. There were 0·84 males (95% UI 0·78-0·91) per female living with HIV in 2019, 0·99 male infections (0·91-1·10) for every female infection, and 1·02 male deaths (0·95-1·10) per female death. Global progress in incident cases and deaths between 2010 and 2019 was driven by sub-Saharan Africa (with a 28·52% decrease in incident cases, 95% UI 19·58-35·43, and a 39·66% decrease in deaths, 36·49-42·36). Elsewhere, the incidence remained stable or increased, whereas deaths generally decreased. In 2019, the global incidence-to-prevalence ratio was 0·05 (95% UI 0·05-0·06) and the global incidence-to-mortality ratio was 1·94 (1·76-2·12). No regions met suggested thresholds for progress. INTERPRETATION: Sub-Saharan Africa had both the highest HIV burden and the greatest progress between 1990 and 2019. The number of incident cases and deaths in males and females approached parity in 2019, although there remained more females with HIV than males with HIV. Globally, the HIV epidemic is far from the UNAIDS benchmarks on progress metrics. FUNDING: The Bill & Melinda Gates Foundation, the National Institute of Mental Health of the US National Institutes of Health (NIH), and the National Institute on Aging of the NIH.
| Original language | English |
|---|---|
| Pages (from-to) | e633-e651 |
| Number of pages | 19 |
| Journal | The Lancet HIV |
| Volume | 8 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 1 Oct 2021 |
Keywords
- Sex-Specific Burden
- HIV
- Epidemic
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Global, regional, and national sex-specific burden and control of the HIV epidemic, 1990–2019, for 204 countries and territories : the Global Burden of Diseases Study 2019. / GBD 2019 HIV Collaborators; Jahagirdar, Deepa; Walters, Magdalene K; Novotney, Amanda ; Brewer, Edmond D; Frank, Tahvi; Carter, Austin; Biehl, Molly H.; Abbastabar, Hedayat; Abhilash, E S ; Abu-Gharbieh, Eman; Abu-Raddad, Laith Jamal; Adekanmbi, Victor; Adedayo Adeyinka, Daniel; Adnani, Qorinah Estininhtyas Sakilah; Afzal, Saira; Aghababaei, Soodabeh; Ahinkorah, Bright Opoku; Ahmad, Sajjad; Ahmadi, Keivan; Ahmadi, Sepideh; Ahmadpour, Ehsan; Ahmed, Muktar Beshir; Rashid, Tarik Ahmed; Salih, Yusra Ahmed; Aklilu, Addis; Akram, Tayyaba; Akunna, Chisom Joyqueenet; Al Hamad, Hanadi ; Alahdab, Fares; Alanezi, Fahad Mashhour; Aleksandrova, Ekaterina A; Alene, Kefyalew Addis; Ali, Liaqat; Alipour, Vahid; Almustanyir, Sami; Alvis-Guzman, Nelson; Ameyaw, Edward Kwabena; Amu, Hubert; Andrei, Catalina Liliana; Andrei, Tudorel; Anvari, Davood; Arabloo, Jalal; Aremu, Olatunde; Arulappan, Judie; Atnafu, Desta Debalkie; Quintanilla, Beatriz Paulina Ayala; Ayza, Muluken Altaye; Azari, Samad; B, Darshan B.; Banach, Maciej; Barnighausen, Till Winfried; Barra, Fabio; Barrow, Amadou; Basu, Sanjay; Bazargan-Hejazi, Shahrzad; Belay, Habtamu Gebrehana; Berheto, Tezera Moshago; Bezabhe, Woldesellassie Mequanint; Bezabih, Yihienew Mequanint; Bhagavathula, Akshaya Srikanth; Bhardwaj, Nikha; Bhardwaj, Pankaj; Bhattacharyya, Krittika; Bibi, Sadia; Bijani, Ali; Bisignano, Catherine; Bolarinwa, Obasanjo Afolabi; Boloor, Archith; Boltaev, Azizbek A; Briko, Nikolay Ivanovich; Buonsenso, Danilo; Burkart, Katrin; Butt, Zahid A.; Cao, Chao; Charan, Jaykaran; Chatterjee, Souranshu; Chattu, Soosanna Kumary; Chattu, Vijay Kumar; Choudhari, Sonali Gajanan; Chu, Dinh Toi; Couto, Rosa A S; Cowden, Richard G.; Dachew, Berihun Assefa; Dadras, Omid; Dagnew, Amare Belachew; Dahlawi, Saad M.A.; Dai, Xiaochen; Dandona, Lalit; Dandona, Rakhi; Neves, José Das; Degenhardt, Louisa; Demeke, Feleke Mekonnen; Desta, Abebaw Alemayehu; Deuba, Keshab; Dhamnetiya, Deepak; Dhungana, Govinda Prasad; Dianatinasab, Mostafa; Diaz, Daniel; Djalalinia, Shirin; Doan, Linh Phuong; Dorostkar, Fariba; Edinur, Hisham Atan; Effiong, Andem; Eftekharzadeh, Sahar; El Sayed Zaki, Maysaa; Elayedath, Rajesh; Elhadi, Muhammed ; El-Jaafary, Shaimaa I.; El-Khatib, Ziad; Elsharkawy, Aisha; Endalamaw, Aklilu; Endries, Aman Yesuf; Eskandarieh, Sharareh; Ezeonwumelu, Ifeanyi Jude ; Ezzikouri, Sayeh; Farahmand, Mohammad; Jose A Faraon, Emerito; Fasanmi, Abidemi Omolara ; Ferrero, Simone; Ferro Desideri, Lorenzo; Filip, Irina; Fischer, Florian; Folayan, Morenike Oluwatoyin; Foroutan, Masoud; Fukumoto, Takeshi; Gad, Mohamed M.; Gadanya, Muktar A; Gaidhane, Abhay Motiramji; Garg, Tushar ; Gayesa, Reta Tsegaye; Gebreyohannes, Eyob Alemayehu ; Obsa, Abera Getachew; Ghadiri, Keyghobad; Ghashghaee, Ahmad; Gilani, Syed Amir; Ginindza, Themba T.G.; Glăvan, Ionela-Roxana ; Glushkova, Ekaterina Vladimirovna; Golechha, Mahaveer; Gugnani, Harish Chander; Gupta, Bhawna; Gupta, Sapna; Gupta, Veer Bala; Gupta, Vivek Kumar; Hamidi, Samer; Handanagic, Senad; Haque, Shafiul; Harapan, Harapan; Hargono, Arief; Hasaballah, Ahmed I.; Hashi, Abdiwahab; Hassan, Shoaib; Hassanipour, Soheil; Hayat, Khezar; Heredia-Pi, Ileana; Hezam, Kamal; Holla, Ramesh; Hoogar, Praveen; Hoque, Mohammad Enamul ; Hosseini, Mostafa; Hosseinzadeh, Medhi ; Hsairi, Mohamed; Hussain, Rabia; Ibitoye, Segun Emmanuel; Idrisov, Bulat; Ikuta, Kevin S.; Ilesanmi, Olayinka Stephen; Ilic, Irena M.; Ilic, Milena D.; Irvani, Seyed Sina Naghibi; Islam, M Mifizul; Ismail, Nahlah Elkudssiah; Itumalla, Ramaiah; Iyamu, Ihoghosa Osamuyi; Jabbarinejad, Roxanna; Jain, Vardhmaan; Jayawardena, Ranil; Jha, Ravi Prakash; Joseph, Nitin; Kabir, Ali; Kabir, Zubair; Kalhor, Rohollah; Kaliyadan, Feroze ; Kamath, Ashwin; Kanchan, Tanuj; Kandel, Himal; Kassahun, Getinet; Katoto, Patrick DMC; Kayode, Gbenga A.; Kebede, Ermiyas Mulu; Kebede, Hafte Kahsay; Khajuria, Himanshu; Khalid, Nauman; Khan, Ejaz Ahmad; Khan, Gulfaraz; Khatab, Khaled; Kim, Min Seo; Kim, Yun Jin; Kisa, Adnan; Kisa, Sezer; Kochhar, Sonali; Korshunov, Vladimir Andreevich; Koul, Parvaiz A.; Koulmane Laxminarayana, SindhuraLakshmi ; Koyanagi, Ai; Krishan, Kewal; Kuate Defo, Barthelemy; Kumar, G. Anil; Kumar, Manasi; Kumar, Nithin; Kwarteng, Alexander; Lal, Dharmesh K.; Landires, Iván; Lasrado, Savita; Lassi, Zohra S.; Lazarus, Jeffrey V; Lee, Jane Jean Hee; Lee, Yeong Yeh; LeGrand, Kate E.; Lin, Christine; Liu, Xuefeng; Maddison, Emilie R.; Abd El Razek, Hassan Magdy; Mahasha, Phetole Walter; Majeed, Azeem; Makki, Alaa; Malik, Ahmad Azam; Manamo, Wondimu Ayele; Mansournia, Mohammad Ali; Martins-Melo, Francisco Rogerlândio; Masoumi, Seyedeh Zahra; Memish, Ziad A; Menezes, Ritesh G.; Mengesha, Endalkachew Worku; Merie, Hayimro Edemealem; Mersha, Amanual Getnet; Mestrovic, Tomislav; Meylakhs, Peter ; Mheidly, Nour ; Miller, Ted R.; Mirica, Andreea; Moazen, Babak; Mohammad, Yousef; Mwanri, Lillian; Tesfay, Fisaha Haile; Ward, Paul; Mpundu-Kaambwa, Christine; Mohammadi, Mokhtar; Yadav, Lalit.
In: The Lancet HIV, Vol. 8, No. 10, 01.10.2021, p. e633-e651.Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - Global, regional, and national sex-specific burden and control of the HIV epidemic, 1990–2019, for 204 countries and territories
T2 - the Global Burden of Diseases Study 2019
AU - GBD 2019 HIV Collaborators
AU - Jahagirdar, Deepa
AU - Walters, Magdalene K
AU - Novotney, Amanda
AU - Brewer, Edmond D
AU - Frank, Tahvi
AU - Carter, Austin
AU - Biehl, Molly H.
AU - Abbastabar, Hedayat
AU - Abhilash, E S
AU - Abu-Gharbieh, Eman
AU - Abu-Raddad, Laith Jamal
AU - Adekanmbi, Victor
AU - Adedayo Adeyinka, Daniel
AU - Adnani, Qorinah Estininhtyas Sakilah
AU - Afzal, Saira
AU - Aghababaei, Soodabeh
AU - Ahinkorah, Bright Opoku
AU - Ahmad, Sajjad
AU - Ahmadi, Keivan
AU - Ahmadi, Sepideh
AU - Ahmadpour, Ehsan
AU - Ahmed, Muktar Beshir
AU - Rashid, Tarik Ahmed
AU - Salih, Yusra Ahmed
AU - Aklilu, Addis
AU - Akram, Tayyaba
AU - Akunna, Chisom Joyqueenet
AU - Al Hamad, Hanadi
AU - Alahdab, Fares
AU - Alanezi, Fahad Mashhour
AU - Aleksandrova, Ekaterina A
AU - Alene, Kefyalew Addis
AU - Ali, Liaqat
AU - Alipour, Vahid
AU - Almustanyir, Sami
AU - Alvis-Guzman, Nelson
AU - Ameyaw, Edward Kwabena
AU - Amu, Hubert
AU - Andrei, Catalina Liliana
AU - Andrei, Tudorel
AU - Anvari, Davood
AU - Arabloo, Jalal
AU - Aremu, Olatunde
AU - Arulappan, Judie
AU - Atnafu, Desta Debalkie
AU - Quintanilla, Beatriz Paulina Ayala
AU - Ayza, Muluken Altaye
AU - Azari, Samad
AU - B, Darshan B.
AU - Banach, Maciej
AU - Barnighausen, Till Winfried
AU - Barra, Fabio
AU - Barrow, Amadou
AU - Basu, Sanjay
AU - Bazargan-Hejazi, Shahrzad
AU - Belay, Habtamu Gebrehana
AU - Berheto, Tezera Moshago
AU - Bezabhe, Woldesellassie Mequanint
AU - Bezabih, Yihienew Mequanint
AU - Bhagavathula, Akshaya Srikanth
AU - Bhardwaj, Nikha
AU - Bhardwaj, Pankaj
AU - Bhattacharyya, Krittika
AU - Bibi, Sadia
AU - Bijani, Ali
AU - Bisignano, Catherine
AU - Bolarinwa, Obasanjo Afolabi
AU - Boloor, Archith
AU - Boltaev, Azizbek A
AU - Briko, Nikolay Ivanovich
AU - Buonsenso, Danilo
AU - Burkart, Katrin
AU - Butt, Zahid A.
AU - Cao, Chao
AU - Charan, Jaykaran
AU - Chatterjee, Souranshu
AU - Chattu, Soosanna Kumary
AU - Chattu, Vijay Kumar
AU - Choudhari, Sonali Gajanan
AU - Chu, Dinh Toi
AU - Couto, Rosa A S
AU - Cowden, Richard G.
AU - Dachew, Berihun Assefa
AU - Dadras, Omid
AU - Dagnew, Amare Belachew
AU - Dahlawi, Saad M.A.
AU - Dai, Xiaochen
AU - Dandona, Lalit
AU - Dandona, Rakhi
AU - Neves, José Das
AU - Degenhardt, Louisa
AU - Demeke, Feleke Mekonnen
AU - Desta, Abebaw Alemayehu
AU - Deuba, Keshab
AU - Dhamnetiya, Deepak
AU - Dhungana, Govinda Prasad
AU - Dianatinasab, Mostafa
AU - Diaz, Daniel
AU - Djalalinia, Shirin
AU - Doan, Linh Phuong
AU - Dorostkar, Fariba
AU - Edinur, Hisham Atan
AU - Effiong, Andem
AU - Eftekharzadeh, Sahar
AU - El Sayed Zaki, Maysaa
AU - Elayedath, Rajesh
AU - Elhadi, Muhammed
AU - El-Jaafary, Shaimaa I.
AU - El-Khatib, Ziad
AU - Elsharkawy, Aisha
AU - Endalamaw, Aklilu
AU - Endries, Aman Yesuf
AU - Eskandarieh, Sharareh
AU - Ezeonwumelu, Ifeanyi Jude
AU - Ezzikouri, Sayeh
AU - Farahmand, Mohammad
AU - Jose A Faraon, Emerito
AU - Fasanmi, Abidemi Omolara
AU - Ferrero, Simone
AU - Ferro Desideri, Lorenzo
AU - Filip, Irina
AU - Fischer, Florian
AU - Folayan, Morenike Oluwatoyin
AU - Foroutan, Masoud
AU - Fukumoto, Takeshi
AU - Gad, Mohamed M.
AU - Gadanya, Muktar A
AU - Gaidhane, Abhay Motiramji
AU - Garg, Tushar
AU - Gayesa, Reta Tsegaye
AU - Gebreyohannes, Eyob Alemayehu
AU - Gesesew, Hailay Abrha
AU - Obsa, Abera Getachew
AU - Ghadiri, Keyghobad
AU - Ghashghaee, Ahmad
AU - Gilani, Syed Amir
AU - Ginindza, Themba T.G.
AU - Glăvan, Ionela-Roxana
AU - Glushkova, Ekaterina Vladimirovna
AU - Golechha, Mahaveer
AU - Gugnani, Harish Chander
AU - Gupta, Bhawna
AU - Gupta, Sapna
AU - Gupta, Veer Bala
AU - Gupta, Vivek Kumar
AU - Hamidi, Samer
AU - Handanagic, Senad
AU - Haque, Shafiul
AU - Harapan, Harapan
AU - Hargono, Arief
AU - Hasaballah, Ahmed I.
AU - Hashi, Abdiwahab
AU - Hassan, Shoaib
AU - Hassanipour, Soheil
AU - Hayat, Khezar
AU - Heredia-Pi, Ileana
AU - Hezam, Kamal
AU - Holla, Ramesh
AU - Hoogar, Praveen
AU - Hoque, Mohammad Enamul
AU - Hosseini, Mostafa
AU - Hosseinzadeh, Medhi
AU - Hsairi, Mohamed
AU - Hussain, Rabia
AU - Ibitoye, Segun Emmanuel
AU - Idrisov, Bulat
AU - Ikuta, Kevin S.
AU - Ilesanmi, Olayinka Stephen
AU - Ilic, Irena M.
AU - Ilic, Milena D.
AU - Irvani, Seyed Sina Naghibi
AU - Islam, M Mifizul
AU - Ismail, Nahlah Elkudssiah
AU - Itumalla, Ramaiah
AU - Iyamu, Ihoghosa Osamuyi
AU - Jabbarinejad, Roxanna
AU - Jain, Vardhmaan
AU - Jayawardena, Ranil
AU - Jha, Ravi Prakash
AU - Joseph, Nitin
AU - Kabir, Ali
AU - Kabir, Zubair
AU - Kalhor, Rohollah
AU - Kaliyadan, Feroze
AU - Kamath, Ashwin
AU - Kanchan, Tanuj
AU - Kandel, Himal
AU - Kassahun, Getinet
AU - Katoto, Patrick DMC
AU - Kayode, Gbenga A.
AU - Kebede, Ermiyas Mulu
AU - Kebede, Hafte Kahsay
AU - Khajuria, Himanshu
AU - Khalid, Nauman
AU - Khan, Ejaz Ahmad
AU - Khan, Gulfaraz
AU - Khatab, Khaled
AU - Kim, Min Seo
AU - Kim, Yun Jin
AU - Kisa, Adnan
AU - Kisa, Sezer
AU - Kochhar, Sonali
AU - Korshunov, Vladimir Andreevich
AU - Koul, Parvaiz A.
AU - Koulmane Laxminarayana, SindhuraLakshmi
AU - Koyanagi, Ai
AU - Krishan, Kewal
AU - Kuate Defo, Barthelemy
AU - Kumar, G. Anil
AU - Kumar, Manasi
AU - Kumar, Nithin
AU - Kwarteng, Alexander
AU - Lal, Dharmesh K.
AU - Landires, Iván
AU - Lasrado, Savita
AU - Lassi, Zohra S.
AU - Lazarus, Jeffrey V
AU - Lee, Jane Jean Hee
AU - Lee, Yeong Yeh
AU - LeGrand, Kate E.
AU - Lin, Christine
AU - Liu, Xuefeng
AU - Maddison, Emilie R.
AU - Abd El Razek, Hassan Magdy
AU - Mahasha, Phetole Walter
AU - Majeed, Azeem
AU - Makki, Alaa
AU - Malik, Ahmad Azam
AU - Manamo, Wondimu Ayele
AU - Mansournia, Mohammad Ali
AU - Martins-Melo, Francisco Rogerlândio
AU - Masoumi, Seyedeh Zahra
AU - Memish, Ziad A
AU - Menezes, Ritesh G.
AU - Mengesha, Endalkachew Worku
AU - Merie, Hayimro Edemealem
AU - Mersha, Amanual Getnet
AU - Mestrovic, Tomislav
AU - Meylakhs, Peter
AU - Mheidly, Nour
AU - Miller, Ted R.
AU - Mirica, Andreea
AU - Moazen, Babak
AU - Mohammad, Yousef
AU - Mwanri, Lillian
AU - Tesfay, Fisaha Haile
AU - Ward, Paul
AU - Mpundu-Kaambwa, Christine
AU - Mohammadi, Mokhtar
AU - Yadav, Lalit
PY - 2021/10/1
Y1 - 2021/10/1
N2 - BACKGROUND: The sustainable development goals (SDGs) aim to end HIV/AIDS as a public health threat by 2030. Understanding the current state of the HIV epidemic and its change over time is essential to this effort. This study assesses the current sex-specific HIV burden in 204 countries and territories and measures progress in the control of the epidemic. METHODS: To estimate age-specific and sex-specific trends in 48 of 204 countries, we extended the Estimation and Projection Package Age-Sex Model to also implement the spectrum paediatric model. We used this model in cases where age and sex specific HIV-seroprevalence surveys and antenatal care-clinic sentinel surveillance data were available. For the remaining 156 of 204 locations, we developed a cohort-incidence bias adjustment to derive incidence as a function of cause-of-death data from vital registration systems. The incidence was input to a custom Spectrum model. To assess progress, we measured the percentage change in incident cases and deaths between 2010 and 2019 (threshold >75% decline), the ratio of incident cases to number of people living with HIV (incidence-to-prevalence ratio threshold <0·03), and the ratio of incident cases to deaths (incidence-to-mortality ratio threshold <1·0). FINDINGS: In 2019, there were 36·8 million (95% uncertainty interval [UI] 35·1-38·9) people living with HIV worldwide. There were 0·84 males (95% UI 0·78-0·91) per female living with HIV in 2019, 0·99 male infections (0·91-1·10) for every female infection, and 1·02 male deaths (0·95-1·10) per female death. Global progress in incident cases and deaths between 2010 and 2019 was driven by sub-Saharan Africa (with a 28·52% decrease in incident cases, 95% UI 19·58-35·43, and a 39·66% decrease in deaths, 36·49-42·36). Elsewhere, the incidence remained stable or increased, whereas deaths generally decreased. In 2019, the global incidence-to-prevalence ratio was 0·05 (95% UI 0·05-0·06) and the global incidence-to-mortality ratio was 1·94 (1·76-2·12). No regions met suggested thresholds for progress. INTERPRETATION: Sub-Saharan Africa had both the highest HIV burden and the greatest progress between 1990 and 2019. The number of incident cases and deaths in males and females approached parity in 2019, although there remained more females with HIV than males with HIV. Globally, the HIV epidemic is far from the UNAIDS benchmarks on progress metrics. FUNDING: The Bill & Melinda Gates Foundation, the National Institute of Mental Health of the US National Institutes of Health (NIH), and the National Institute on Aging of the NIH.
AB - BACKGROUND: The sustainable development goals (SDGs) aim to end HIV/AIDS as a public health threat by 2030. Understanding the current state of the HIV epidemic and its change over time is essential to this effort. This study assesses the current sex-specific HIV burden in 204 countries and territories and measures progress in the control of the epidemic. METHODS: To estimate age-specific and sex-specific trends in 48 of 204 countries, we extended the Estimation and Projection Package Age-Sex Model to also implement the spectrum paediatric model. We used this model in cases where age and sex specific HIV-seroprevalence surveys and antenatal care-clinic sentinel surveillance data were available. For the remaining 156 of 204 locations, we developed a cohort-incidence bias adjustment to derive incidence as a function of cause-of-death data from vital registration systems. The incidence was input to a custom Spectrum model. To assess progress, we measured the percentage change in incident cases and deaths between 2010 and 2019 (threshold >75% decline), the ratio of incident cases to number of people living with HIV (incidence-to-prevalence ratio threshold <0·03), and the ratio of incident cases to deaths (incidence-to-mortality ratio threshold <1·0). FINDINGS: In 2019, there were 36·8 million (95% uncertainty interval [UI] 35·1-38·9) people living with HIV worldwide. There were 0·84 males (95% UI 0·78-0·91) per female living with HIV in 2019, 0·99 male infections (0·91-1·10) for every female infection, and 1·02 male deaths (0·95-1·10) per female death. Global progress in incident cases and deaths between 2010 and 2019 was driven by sub-Saharan Africa (with a 28·52% decrease in incident cases, 95% UI 19·58-35·43, and a 39·66% decrease in deaths, 36·49-42·36). Elsewhere, the incidence remained stable or increased, whereas deaths generally decreased. In 2019, the global incidence-to-prevalence ratio was 0·05 (95% UI 0·05-0·06) and the global incidence-to-mortality ratio was 1·94 (1·76-2·12). No regions met suggested thresholds for progress. INTERPRETATION: Sub-Saharan Africa had both the highest HIV burden and the greatest progress between 1990 and 2019. The number of incident cases and deaths in males and females approached parity in 2019, although there remained more females with HIV than males with HIV. Globally, the HIV epidemic is far from the UNAIDS benchmarks on progress metrics. FUNDING: The Bill & Melinda Gates Foundation, the National Institute of Mental Health of the US National Institutes of Health (NIH), and the National Institute on Aging of the NIH.
KW - Sex-Specific Burden
KW - HIV
KW - Epidemic
UR - http://purl.org/au-research/grants/NHMRC/1135991
UR - http://purl.org/au-research/grants/NHMRC/1195716
UR - http://www.scopus.com/inward/record.url?scp=85117526510&partnerID=8YFLogxK
U2 - 10.1016/S2352-3018(21)00152-1
DO - 10.1016/S2352-3018(21)00152-1
M3 - Article
VL - 8
SP - e633-e651
JO - The Lancet HIV
JF - The Lancet HIV
SN - 2352-3018
IS - 10
ER -