Gut microbial biomarkers for predicting adverse outcomes in people with chronic kidney disease

Tess E. Cooper; Eric H. Au; Edmund Y.M. Chung; David J. Tunnicliffe; Jonathan C. Craig; Loreto Gesualdo; Martin Howell; Peter Mannon; Roslyn Mannon; Giovanni F. M. Strippoli; Armando Teixeira-Pinto; Allison Tong; Germaine Wong

doi:10.1002/14651858.CD014786

Gut microbial biomarkers for predicting adverse outcomes in people with chronic kidney disease

Tess E. Cooper, Eric H. Au, Edmund Y.M. Chung, David J. Tunnicliffe, Jonathan C. Craig, Loreto Gesualdo, Martin Howell, Peter Mannon, Roslyn Mannon, Giovanni F. M. Strippoli, Armando Teixeira-Pinto, Allison Tong, Germaine Wong

College of Medicine and Public Health

Research output: Contribution to journal › Review article › peer-review

Abstract

Objectives: This is a protocol for a Cochrane Review (prognosis). The objectives are as follows:. To (a) identify the gut microbial biomarkers in patients with CKD, on dialysis, and with kidney transplants; (b) determine whether these biomarkers are associated independently with adverse patient-relevant outcomes leading to progression of CKD stages 1 to 5; and (c) explore sources of heterogeneity. Investigation of sources of heterogeneity between studies We will explore potential sources of heterogeneity that may impact outcomes such as differences in study participation; stage of CKD (KDIGO 2013; Appendix 1); study design (cohort, case series, case study), timing of outcome measurements; units and instruments of outcome measurements; and length of follow-up.

Original language	English
Article number	CD014786
Number of pages	20
Journal	Cochrane Database of Systematic Reviews
Issue number	1
DOIs	https://doi.org/10.1002/14651858.CD014786
Publication status	Published - 12 Jan 2022

Keywords

Gut
microbial
biomarkers
chronic
kidney
disease

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/14651858.CD014786Licence: In Copyright

Cite this

Cooper, T. E., Au, E. H., Chung, E. Y. M., Tunnicliffe, D. J., Craig, J. C., Gesualdo, L., Howell, M., Mannon, P., Mannon, R., Strippoli, G. F. M., Teixeira-Pinto, A., Tong, A., & Wong, G. (2022). Gut microbial biomarkers for predicting adverse outcomes in people with chronic kidney disease. Cochrane Database of Systematic Reviews, (1), Article CD014786. https://doi.org/10.1002/14651858.CD014786

@article{b6fb36f709834f959755d37a6a3e62e6,

title = "Gut microbial biomarkers for predicting adverse outcomes in people with chronic kidney disease",

abstract = "Objectives: This is a protocol for a Cochrane Review (prognosis). The objectives are as follows:. To (a) identify the gut microbial biomarkers in patients with CKD, on dialysis, and with kidney transplants; (b) determine whether these biomarkers are associated independently with adverse patient-relevant outcomes leading to progression of CKD stages 1 to 5; and (c) explore sources of heterogeneity. Investigation of sources of heterogeneity between studies We will explore potential sources of heterogeneity that may impact outcomes such as differences in study participation; stage of CKD (KDIGO 2013; Appendix 1); study design (cohort, case series, case study), timing of outcome measurements; units and instruments of outcome measurements; and length of follow-up.",

keywords = "Gut, microbial, biomarkers, chronic, kidney, disease",

author = "Cooper, {Tess E.} and Au, {Eric H.} and Chung, {Edmund Y.M.} and Tunnicliffe, {David J.} and Craig, {Jonathan C.} and Loreto Gesualdo and Martin Howell and Peter Mannon and Roslyn Mannon and Strippoli, {Giovanni F. M.} and Armando Teixeira-Pinto and Allison Tong and Germaine Wong",

year = "2022",

month = jan,

day = "12",

doi = "10.1002/14651858.CD014786",

language = "English",

journal = "Cochrane Database of Systematic Reviews",

issn = "1465-1858",

publisher = "John Wiley & Sons Ltd",

number = "1",

}

TY - JOUR

T1 - Gut microbial biomarkers for predicting adverse outcomes in people with chronic kidney disease

AU - Cooper, Tess E.

AU - Au, Eric H.

AU - Chung, Edmund Y.M.

AU - Tunnicliffe, David J.

AU - Craig, Jonathan C.

AU - Gesualdo, Loreto

AU - Howell, Martin

AU - Mannon, Peter

AU - Mannon, Roslyn

AU - Strippoli, Giovanni F. M.

AU - Teixeira-Pinto, Armando

AU - Tong, Allison

AU - Wong, Germaine

PY - 2022/1/12

Y1 - 2022/1/12

N2 - Objectives: This is a protocol for a Cochrane Review (prognosis). The objectives are as follows:. To (a) identify the gut microbial biomarkers in patients with CKD, on dialysis, and with kidney transplants; (b) determine whether these biomarkers are associated independently with adverse patient-relevant outcomes leading to progression of CKD stages 1 to 5; and (c) explore sources of heterogeneity. Investigation of sources of heterogeneity between studies We will explore potential sources of heterogeneity that may impact outcomes such as differences in study participation; stage of CKD (KDIGO 2013; Appendix 1); study design (cohort, case series, case study), timing of outcome measurements; units and instruments of outcome measurements; and length of follow-up.

AB - Objectives: This is a protocol for a Cochrane Review (prognosis). The objectives are as follows:. To (a) identify the gut microbial biomarkers in patients with CKD, on dialysis, and with kidney transplants; (b) determine whether these biomarkers are associated independently with adverse patient-relevant outcomes leading to progression of CKD stages 1 to 5; and (c) explore sources of heterogeneity. Investigation of sources of heterogeneity between studies We will explore potential sources of heterogeneity that may impact outcomes such as differences in study participation; stage of CKD (KDIGO 2013; Appendix 1); study design (cohort, case series, case study), timing of outcome measurements; units and instruments of outcome measurements; and length of follow-up.

KW - Gut

KW - microbial

KW - biomarkers

KW - chronic

KW - kidney

KW - disease

UR - http://www.scopus.com/inward/record.url?scp=85122767023&partnerID=8YFLogxK

U2 - 10.1002/14651858.CD014786

DO - 10.1002/14651858.CD014786

M3 - Review article

AN - SCOPUS:85122767023

SN - 1465-1858

JO - Cochrane Database of Systematic Reviews

JF - Cochrane Database of Systematic Reviews

IS - 1

M1 - CD014786

ER -

Gut microbial biomarkers for predicting adverse outcomes in people with chronic kidney disease

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this