Healthcare workers’ experiences of transitioning natalizumab infusions from hospital services to an in-home setting: a qualitative study

Mahasen Juaton, Lynette Cusack, Tim Schultz

Research output: Contribution to journalArticlepeer-review


Objective: This study explored healthcare workers’ experiences of transitioning infusions of natalizumab from hospital to a patient-centred model of home care. Background: Hospital in the home is one of the fastest growing healthcare delivery models. In Australia, intravenous infusions are rarely available at home for chronic disease patients, such as those with multiple sclerosis. A recent trial of natalizumab infusions at home for patients with multiple sclerosis required both the hospital and hospital in the home staff to consider the logistics of how this transition could be achieved safely. Study design and methods: This was a qualitative study using an exploratory-descriptive approach. Twelve participants from two main groups of healthcare workers participated in delivering natalizumab infusions during the six-month trial period and were subsequently interviewed about their experience. Participants were recruited from a hospital ambulatory care day unit and a Home Infusion Team from a private provider of home nursing care located in South Australia. The data was analysed thematically. Results: Three main themes were identified from the interviews: ‘preparing for change’, ‘focussing on the patient’, and ‘enhancing professional support and relationships’. These findings demonstrated the importance of understanding healthcare workers’ experiences of transitioning to a patient-centred model of care, from hospital to home infusion of natalizumab. Discussion: Flexibility and good management of logistics is necessary to maintain the standards of the health services, which highlights the need for training and professional support to facilitate quality home care. This may enhance workers’ sense of professional confidence and trust and reduce stress when delivering the home model of care. Conclusion: Healthcare workers and patients worked to support one another, not only therapeutically but also logistically within collegial relationship and interdependent communications. Being flexible, communicating clearly and being willing to work together within the team, especially between the hospital in the home staff and the hospital staff, was demonstrated to be an important factor for the safe delivery of infusions at home. Managing the logistics of delivering a flexible and safe home therapy service was an important part of this model of care. Implications for research, policy, and practice: The results of this study will be used to inform healthcare teams about the key logistical components that are important for healthcare services, when considering transitioning to a home-based model of care for treating people with relapsing-remitting multiple sclerosis

Original languageEnglish
Article number2020.391.240
Pages (from-to)18-26
Number of pages9
JournalAustralian Journal of Advanced Nursing
Issue number1
Publication statusPublished - Dec 2021
Externally publishedYes


  • Healthcare worker
  • Home infusion
  • Model of care
  • Multiple sclerosis
  • Natalizumab


Dive into the research topics of 'Healthcare workers’ experiences of transitioning natalizumab infusions from hospital services to an in-home setting: a qualitative study'. Together they form a unique fingerprint.

Cite this