HLA DQA1 genotyping of Chinese in Taiwan by PCR-RFLP.

F. S. Lo; J. G. Chang; Y. J. Lee; A. Linacre; J. C. Lee

HLA DQA1 genotyping of Chinese in Taiwan by PCR-RFLP.

F. S. Lo, J. G. Chang, Y. J. Lee, A. Linacre, J. C. Lee

Research output: Contribution to journal › Article › peer-review

Abstract

Population data were established for the HLA DQA1 locus among 147 Chinese in Taiwan by the PCR-RFLP flowchart system. Twelve alleles could be differentiated in this study, although only nine alleles were found among the above samples. There were no discrepancies in the results obtained by PCR-RFLP when compared to the results obtained by the AmpliType HLA DQ alpha typing kit. Using the Chi-square test, significant differences were observed (p < 0.005) between this data and that for Japanese, African Americans and US Caucasians. The observed heterozygosity was 83% with a discrimination power of 0.93.

Original language	English
Pages (from-to)	458-463
Number of pages	6
Journal	The Kaohsiung journal of medical sciences
Volume	14
Issue number	8
Publication status	Published - Aug 1998
Externally published	Yes

Cite this

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title = "HLA DQA1 genotyping of Chinese in Taiwan by PCR-RFLP.",

abstract = "Population data were established for the HLA DQA1 locus among 147 Chinese in Taiwan by the PCR-RFLP flowchart system. Twelve alleles could be differentiated in this study, although only nine alleles were found among the above samples. There were no discrepancies in the results obtained by PCR-RFLP when compared to the results obtained by the AmpliType HLA DQ alpha typing kit. Using the Chi-square test, significant differences were observed (p < 0.005) between this data and that for Japanese, African Americans and US Caucasians. The observed heterozygosity was 83% with a discrimination power of 0.93.",

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AU - Lee, Y. J.

AU - Linacre, A.

AU - Lee, J. C.

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N2 - Population data were established for the HLA DQA1 locus among 147 Chinese in Taiwan by the PCR-RFLP flowchart system. Twelve alleles could be differentiated in this study, although only nine alleles were found among the above samples. There were no discrepancies in the results obtained by PCR-RFLP when compared to the results obtained by the AmpliType HLA DQ alpha typing kit. Using the Chi-square test, significant differences were observed (p < 0.005) between this data and that for Japanese, African Americans and US Caucasians. The observed heterozygosity was 83% with a discrimination power of 0.93.

AB - Population data were established for the HLA DQA1 locus among 147 Chinese in Taiwan by the PCR-RFLP flowchart system. Twelve alleles could be differentiated in this study, although only nine alleles were found among the above samples. There were no discrepancies in the results obtained by PCR-RFLP when compared to the results obtained by the AmpliType HLA DQ alpha typing kit. Using the Chi-square test, significant differences were observed (p < 0.005) between this data and that for Japanese, African Americans and US Caucasians. The observed heterozygosity was 83% with a discrimination power of 0.93.

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JO - The Kaohsiung journal of medical sciences

JF - The Kaohsiung journal of medical sciences

SN - 1607-551X

IS - 8

ER -

HLA DQA1 genotyping of Chinese in Taiwan by PCR-RFLP.

Abstract

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