HLA DQA1 genotyping of Chinese in Taiwan by PCR-RFLP.

F. S. Lo, J. G. Chang, Y. J. Lee, A. Linacre, J. C. Lee

Research output: Contribution to journalArticle

Abstract

Population data were established for the HLA DQA1 locus among 147 Chinese in Taiwan by the PCR-RFLP flowchart system. Twelve alleles could be differentiated in this study, although only nine alleles were found among the above samples. There were no discrepancies in the results obtained by PCR-RFLP when compared to the results obtained by the AmpliType HLA DQ alpha typing kit. Using the Chi-square test, significant differences were observed (p < 0.005) between this data and that for Japanese, African Americans and US Caucasians. The observed heterozygosity was 83% with a discrimination power of 0.93.

Original languageEnglish
Pages (from-to)458-463
Number of pages6
JournalThe Kaohsiung journal of medical sciences
Volume14
Issue number8
Publication statusPublished - Aug 1998
Externally publishedYes

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    Lo, F. S., Chang, J. G., Lee, Y. J., Linacre, A., & Lee, J. C. (1998). HLA DQA1 genotyping of Chinese in Taiwan by PCR-RFLP. The Kaohsiung journal of medical sciences, 14(8), 458-463.