How space dust settles our mind: discovery of the cell and receptor target of the mood stabiliser lithium

DW Thorpe; RA Peterson; A Humenick; Y Ootsuka; WW Blessing; DJ Keating

How space dust settles our mind: discovery of the cell and receptor target of the mood stabiliser lithium

DW Thorpe
, RA Peterson
, A Humenick
, Y Ootsuka
, WW Blessing
, DJ Keating

Research output: Contribution to conference › Abstract

Abstract

Lithium has been a first-line treatment for the manic phase of bipolar disorder for over 70 years. Its primary mechanism, presumed to be in the brain itself, remains unknown. We now present evidence that lithium alters brain function via a primary action in the gut, with modulation of brain function via the gut brain axis.

Original language	English
Number of pages	1
Publication status	Published - Dec 2023
Event	Australasian Society for Autonomic Neuroscience 2023 - University of Queensland, Brisbane, Australia Duration: 2 Dec 2023 → 3 Dec 2023

Conference

Conference	Australasian Society for Autonomic Neuroscience 2023
Abbreviated title	ASAN 2023
Country/Territory	Australia
City	Brisbane
Period	2/12/23 → 3/12/23

Keywords

Mood stabilizer
lithium
brain function
gut brain axis
in vitro study
bipolar disorder

Cite this

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title = "How space dust settles our mind: discovery of the cell and receptor target of the mood stabiliser lithium",

abstract = "Lithium has been a first-line treatment for the manic phase of bipolar disorder for over 70 years. Its primary mechanism, presumed to be in the brain itself, remains unknown. We now present evidence that lithium alters brain function via a primary action in the gut, with modulation of brain function via the gut brain axis. ",

keywords = "Mood stabilizer, lithium, brain function, gut brain axis, in vitro study, bipolar disorder",

author = "DW Thorpe and RA Peterson and A Humenick and Y Ootsuka and WW Blessing and DJ Keating",

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language = "English",

note = "Australasian Society for Autonomic Neuroscience 2023, ASAN 2023 ; Conference date: 02-12-2023 Through 03-12-2023",

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TY - CONF

T1 - How space dust settles our mind: discovery of the cell and receptor target of the mood stabiliser lithium

AU - Thorpe, DW

AU - Peterson, RA

AU - Humenick, A

AU - Ootsuka, Y

AU - Blessing, WW

AU - Keating, DJ

PY - 2023/12

Y1 - 2023/12

N2 - Lithium has been a first-line treatment for the manic phase of bipolar disorder for over 70 years. Its primary mechanism, presumed to be in the brain itself, remains unknown. We now present evidence that lithium alters brain function via a primary action in the gut, with modulation of brain function via the gut brain axis.

AB - Lithium has been a first-line treatment for the manic phase of bipolar disorder for over 70 years. Its primary mechanism, presumed to be in the brain itself, remains unknown. We now present evidence that lithium alters brain function via a primary action in the gut, with modulation of brain function via the gut brain axis.

KW - Mood stabilizer

KW - lithium

KW - brain function

KW - gut brain axis

KW - in vitro study

KW - bipolar disorder

UR - https://australasianautonomic.org/

UR - https://australasianautonomic.org/ws/media-library/8970b94ac8624e5584ad4688036b419e/asan2023-scientific-program.pdf

M3 - Abstract

T2 - Australasian Society for Autonomic Neuroscience 2023

Y2 - 2 December 2023 through 3 December 2023

ER -

How space dust settles our mind: discovery of the cell and receptor target of the mood stabiliser lithium

Abstract

Conference

Keywords

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