How successful is corneal transplantation? a report from the australian corneal graft register

Contributors to the Australian Corneal Graft Registry (ACGR), Keryn A. Williams, Sylvia M. Muehlberg, Rowena F. Lewis, Douglas J. Coster

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    Corneal graft outcome was assessed within a large, prospectively collected database of 4499 records. Penetrating corneal graft survival was 91% at 1 year, 72% at 5 years and 69% at 7 years. The three most common indications for graft were keratoconus (30%), bullous keratopathy (25%) and failed previous graft (18%); the three most common causes of graft failure were rejection (34%), infection (18%) and glaucoma (9%). The vast majority of grafts were performed for improved visual acuity. About four-fifths of recipients achieved at least one line of better acuity on the Snellen chart post-operatively; of the remainder with unchanged or worse acuity, only 21% had failed grafts. Overall, 43% of recipients achieved a best corrected Snellen acuity of 6/12 or better, 52% achieved 6/18 or better, and 20% had acuitities of less than 6/60. Reasons for poorpost-operative acuity (recorded as less than 6/60) included graft failure (41%) and co-morbidities in the grafted eye (43%). A number of risk factors for graft failure were examined: In most instances, there was little room for decision-making or expert intervention.

    Original languageEnglish
    Pages (from-to)219-227
    Number of pages9
    Issue number2
    Publication statusPublished - 1 Mar 1995


    • Corneal transplantation
    • Graft failure
    • Molecular genetics
    • Registry
    • Visual outcome


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