TY - JOUR
T1 - Human T-Lymphotropic Virus type 1 infective dermatitis in central Australia
AU - Einsiedel, Lloyd
AU - Cassar, Olivier
AU - Gordon, Lynne
AU - Gessain, Antoine
PY - 2013/8
Y1 - 2013/8
N2 - The Human T-Lymphotropic Virus type 1 (HTLV-1) is a single-stranded RNA retrovirus that preferentially infects CD4+ T cells. The spectrum of diseases that are associated with the most frequent genotype, the HTLV-1 cosmopolitan subtype A, has been well described. In contrast, very few cases of HTLV-1 related diseases have been reported for the HTLV-1 subtype C variant, which is endemic to Australia and the nearby islands of Melanesia. Here we describe the first case of infective dermatitis associated with the HTLV-1 Australo-Melanesian subtype C. This was complicated by repeated episodes of invasive infection with Staphylococcus aureus and illustrates the life-threatening nature of infective dermatitis among HTLV-1 carriers who live in conditions of social disadvantage.
AB - The Human T-Lymphotropic Virus type 1 (HTLV-1) is a single-stranded RNA retrovirus that preferentially infects CD4+ T cells. The spectrum of diseases that are associated with the most frequent genotype, the HTLV-1 cosmopolitan subtype A, has been well described. In contrast, very few cases of HTLV-1 related diseases have been reported for the HTLV-1 subtype C variant, which is endemic to Australia and the nearby islands of Melanesia. Here we describe the first case of infective dermatitis associated with the HTLV-1 Australo-Melanesian subtype C. This was complicated by repeated episodes of invasive infection with Staphylococcus aureus and illustrates the life-threatening nature of infective dermatitis among HTLV-1 carriers who live in conditions of social disadvantage.
KW - Australia
KW - HTLV-1
KW - HTLV-1 associated infective dermatitis
KW - Indigenous health
UR - http://www.scopus.com/inward/record.url?scp=84879268710&partnerID=8YFLogxK
U2 - 10.1016/j.jcv.2013.04.022
DO - 10.1016/j.jcv.2013.04.022
M3 - Article
SN - 1386-6532
VL - 57
SP - 370
EP - 373
JO - Journal of Clinical Virology
JF - Journal of Clinical Virology
IS - 4
ER -