Human T-Lymphotropic Virus type 1 infective dermatitis in central Australia

Lloyd Einsiedel, Olivier Cassar, Lynne Gordon, Antoine Gessain

    Research output: Contribution to journalArticlepeer-review

    10 Citations (Scopus)

    Abstract

    The Human T-Lymphotropic Virus type 1 (HTLV-1) is a single-stranded RNA retrovirus that preferentially infects CD4+ T cells. The spectrum of diseases that are associated with the most frequent genotype, the HTLV-1 cosmopolitan subtype A, has been well described. In contrast, very few cases of HTLV-1 related diseases have been reported for the HTLV-1 subtype C variant, which is endemic to Australia and the nearby islands of Melanesia. Here we describe the first case of infective dermatitis associated with the HTLV-1 Australo-Melanesian subtype C. This was complicated by repeated episodes of invasive infection with Staphylococcus aureus and illustrates the life-threatening nature of infective dermatitis among HTLV-1 carriers who live in conditions of social disadvantage.

    Original languageEnglish
    Pages (from-to)370-373
    Number of pages4
    JournalJournal of Clinical Virology
    Volume57
    Issue number4
    DOIs
    Publication statusPublished - Aug 2013

    Keywords

    • Australia
    • HTLV-1
    • HTLV-1 associated infective dermatitis
    • Indigenous health

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