Hyponatraemia in heart failure

Su Ling Tee, Andrew Sindone, Simon Roger, John Atherton, John Amerena, Michael D'Emden, Jonathan Erlich, Carmine De Pasquale

    Research output: Contribution to journalReview articlepeer-review

    4 Citations (Scopus)


    Hyponatraemia is common in heart failure (HF). It is estimated that over 20% of patients admitted to hospital with HF have hyponatraemia. It has also been repeatedly shown to be a surrogate marker of increased morbidity and mortality in this specific population. This review focuses on the pathophysiology of hyponatraemia through the activation of neurohormonal cascades in HF, the clinical implications of sustained hyponatraemia and treatment options in the management of this challenging phenomenon.

    Original languageEnglish
    Pages (from-to)659-666
    Number of pages8
    JournalInternal Medicine Journal
    Issue number6
    Publication statusPublished - Jun 2020


    • acute heart failure
    • chronic heart failure
    • hyponatraemia


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