Hypothalamic projections of medullary catecholamine neurons in the rabbit: A combined catecholamine fluorescence and HRP transport study

W. W. Blessing; C. B. Jaeger; D. A. Ruggiero; D. J. Reis

doi:10.1016/0361-9230(82)90141-1

Hypothalamic projections of medullary catecholamine neurons in the rabbit: A combined catecholamine fluorescence and HRP transport study

W. W. Blessing, C. B. Jaeger, D. A. Ruggiero, D. J. Reis

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Abstract

Injections of horseradish peroxidase into the rabbit hypothalamus, centered on the paraventricular nucleus, result in retrograde transport to A1 and A2 neurons in the medulla oblongata, in a bilateral distribution with ipsilateral predominance. Some HRP labeled cells in both A1 and A2 areas do not exhibit a positive histochemical reaction for catecholamines, but, in the Al area, nearly all HRP-positive neurons are catecholamine-containing A1 cells. Injection of radioisotope into the A1 area of the rabbit results in terminal labeling within the paraventricular and supraoptic nuclei. This study complements previous work showing that rabbit A1 and A2 cells have minimal projections to the spinal cord.

Original language	English
Pages (from-to)	279-286
Number of pages	8
Journal	Brain Research Bulletin
Volume	9
Issue number	1-6
DOIs	https://doi.org/10.1016/0361-9230(82)90141-1
Publication status	Published - Jul 1982
Externally published	Yes

Keywords

A1 and A2 catecholamine neurons
Hypertension
Innervation of hypothalamus
Paraventricular and supraoptic nuclei
Rabbit medulla oblongata
Vasopressin

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title = "Hypothalamic projections of medullary catecholamine neurons in the rabbit: A combined catecholamine fluorescence and HRP transport study",

abstract = "Injections of horseradish peroxidase into the rabbit hypothalamus, centered on the paraventricular nucleus, result in retrograde transport to A1 and A2 neurons in the medulla oblongata, in a bilateral distribution with ipsilateral predominance. Some HRP labeled cells in both A1 and A2 areas do not exhibit a positive histochemical reaction for catecholamines, but, in the Al area, nearly all HRP-positive neurons are catecholamine-containing A1 cells. Injection of radioisotope into the A1 area of the rabbit results in terminal labeling within the paraventricular and supraoptic nuclei. This study complements previous work showing that rabbit A1 and A2 cells have minimal projections to the spinal cord.",

keywords = "A1 and A2 catecholamine neurons, Hypertension, Innervation of hypothalamus, Paraventricular and supraoptic nuclei, Rabbit medulla oblongata, Vasopressin",

author = "Blessing, {W. W.} and Jaeger, {C. B.} and Ruggiero, {D. A.} and Reis, {D. J.}",

year = "1982",

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journal = "Brain Research Bulletin",

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T1 - Hypothalamic projections of medullary catecholamine neurons in the rabbit

T2 - A combined catecholamine fluorescence and HRP transport study

AU - Blessing, W. W.

AU - Jaeger, C. B.

AU - Ruggiero, D. A.

AU - Reis, D. J.

PY - 1982/7

Y1 - 1982/7

N2 - Injections of horseradish peroxidase into the rabbit hypothalamus, centered on the paraventricular nucleus, result in retrograde transport to A1 and A2 neurons in the medulla oblongata, in a bilateral distribution with ipsilateral predominance. Some HRP labeled cells in both A1 and A2 areas do not exhibit a positive histochemical reaction for catecholamines, but, in the Al area, nearly all HRP-positive neurons are catecholamine-containing A1 cells. Injection of radioisotope into the A1 area of the rabbit results in terminal labeling within the paraventricular and supraoptic nuclei. This study complements previous work showing that rabbit A1 and A2 cells have minimal projections to the spinal cord.

AB - Injections of horseradish peroxidase into the rabbit hypothalamus, centered on the paraventricular nucleus, result in retrograde transport to A1 and A2 neurons in the medulla oblongata, in a bilateral distribution with ipsilateral predominance. Some HRP labeled cells in both A1 and A2 areas do not exhibit a positive histochemical reaction for catecholamines, but, in the Al area, nearly all HRP-positive neurons are catecholamine-containing A1 cells. Injection of radioisotope into the A1 area of the rabbit results in terminal labeling within the paraventricular and supraoptic nuclei. This study complements previous work showing that rabbit A1 and A2 cells have minimal projections to the spinal cord.

KW - A1 and A2 catecholamine neurons

KW - Hypertension

KW - Innervation of hypothalamus

KW - Paraventricular and supraoptic nuclei

KW - Rabbit medulla oblongata

KW - Vasopressin

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JO - Brain Research Bulletin

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IS - 1-6

ER -

Hypothalamic projections of medullary catecholamine neurons in the rabbit: A combined catecholamine fluorescence and HRP transport study

Abstract

Keywords

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