Identification and cloning of a novel GOLGA4-JAK2 fusion from an adult patient with B-cell acute lymphoblastic leukaemia

Charlotte EJ Downes; Barbara J McClure; Sue  Heatley; Teresa Sadras; Timothy P Hughes; Chung H Kok; David T Yeung; Deborah L White

Identification and cloning of a novel GOLGA4-JAK2 fusion from an adult patient with B-cell acute lymphoblastic leukaemia

Charlotte EJ Downes, Barbara J McClure, Sue Heatley, Teresa Sadras, Timothy P Hughes, Chung H Kok, David T Yeung, Deborah L White

Research output: Contribution to conference › Poster

Abstract

B-cell Acute Lymphoblastic Leukaemia (B-ALL) is a malignant neoplasm of B-cell precursors in the bone marrow and blood. Next generation sequencing has the potential to improve risk stratification and treatment approaches for B-ALL patients. Using this approach, causative genetic lesions in various kinase and cytokine receptor signalling molecules have been identified, some of which are targetable using rational therapies.

Original language	English
Number of pages	1
Publication status	Published - Jun 2017
Externally published	Yes
Event	Australian Society for Medical Research (ASMR) SA Meeting 2017 - Adelaide, Australia Duration: 26 Jun 2017 → …

Conference

Conference	Australian Society for Medical Research (ASMR) SA Meeting 2017
Abbreviated title	ASMR SA Meeting 2017
Country/Territory	Australia
City	Adelaide
Period	26/06/17 → …

Keywords

Identification
Cloning
Lymphoblastic Leukaemia

Cite this

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title = "Identification and cloning of a novel GOLGA4-JAK2 fusion from an adult patient with B-cell acute lymphoblastic leukaemia",

abstract = "B-cell Acute Lymphoblastic Leukaemia (B-ALL) is a malignant neoplasm of B-cell precursors in the bone marrow and blood. Next generation sequencing has the potential to improve risk stratification and treatment approaches for B-ALL patients. Using this approach, causative genetic lesions in various kinase and cytokine receptor signalling molecules have been identified, some of which are targetable using rational therapies.",

keywords = "Identification, Cloning, Lymphoblastic Leukaemia",

author = "Downes, {Charlotte EJ} and McClure, {Barbara J} and Sue Heatley and Teresa Sadras and Hughes, {Timothy P} and Kok, {Chung H} and Yeung, {David T} and White, {Deborah L}",

year = "2017",

month = jun,

language = "English",

note = "Australian Society for Medical Research (ASMR) SA Meeting 2017, ASMR SA Meeting 2017 ; Conference date: 26-06-2017",

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TY - CONF

T1 - Identification and cloning of a novel GOLGA4-JAK2 fusion from an adult patient with B-cell acute lymphoblastic leukaemia

AU - Downes, Charlotte EJ

AU - McClure, Barbara J

AU - Heatley, Sue

AU - Sadras, Teresa

AU - Hughes, Timothy P

AU - Kok, Chung H

AU - Yeung, David T

AU - White, Deborah L

PY - 2017/6

Y1 - 2017/6

N2 - B-cell Acute Lymphoblastic Leukaemia (B-ALL) is a malignant neoplasm of B-cell precursors in the bone marrow and blood. Next generation sequencing has the potential to improve risk stratification and treatment approaches for B-ALL patients. Using this approach, causative genetic lesions in various kinase and cytokine receptor signalling molecules have been identified, some of which are targetable using rational therapies.

AB - B-cell Acute Lymphoblastic Leukaemia (B-ALL) is a malignant neoplasm of B-cell precursors in the bone marrow and blood. Next generation sequencing has the potential to improve risk stratification and treatment approaches for B-ALL patients. Using this approach, causative genetic lesions in various kinase and cytokine receptor signalling molecules have been identified, some of which are targetable using rational therapies.

KW - Identification

KW - Cloning

KW - Lymphoblastic Leukaemia

M3 - Poster

T2 - Australian Society for Medical Research (ASMR) SA Meeting 2017

Y2 - 26 June 2017

ER -

Identification and cloning of a novel GOLGA4-JAK2 fusion from an adult patient with B-cell acute lymphoblastic leukaemia

Abstract

Conference

Keywords

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Cite this