Identification, Review, and Use of Health State Utilities in Cost-Effectiveness Models: An ISPOR Good Practices for Outcomes Research Task Force Report

John Brazier; Roberta Ara; Ismail Azzabi; Jan Busschbach; Hélène Chevrou-Séverac; Bruce Crawford; Luciane Cruz; John Karnon; Andrew Lloyd; Suzy Paisley; A. Simon Pickard

doi:10.1016/j.jval.2019.01.004

Identification, Review, and Use of Health State Utilities in Cost-Effectiveness Models: An ISPOR Good Practices for Outcomes Research Task Force Report

John Brazier, Roberta Ara, Ismail Azzabi, Jan Busschbach, Hélène Chevrou-Séverac, Bruce Crawford, Luciane Cruz, John Karnon, Andrew Lloyd, Suzy Paisley, A. Simon Pickard

Research output: Contribution to journal › Article › peer-review

84 Citations (Scopus)

Abstract

Cost-effectiveness models that present results in terms of cost per quality-adjusted life-year for health technologies are used to inform policy decisions in many parts of the world. Health state utilities (HSUs) are required to calculate the quality-adjusted life-years. Even when clinical studies assessing the effectiveness of health technologies collect data on HSUs to populate a cost-effectiveness model, which rarely happens, analysts typically need to identify at least some additional HSUs from alternative sources. When possible, HSUs are identified by a systematic review of the literature, but, again, this rarely happens. In 2014, ISPOR established a Good Practices for Outcome Research Task Force to address the use of HSUs in cost-effectiveness models. This task force report provides recommendations for researchers who identify, review, and synthesize HSUs for use in cost-effectiveness models; analysts who use the results in models; and reviewers who critically appraise the suitability and validity of the HSUs selected for use in models. The associated Minimum Reporting Standards of Systematic Review of Utilities for Cost-Effectiveness checklist created by the task force provides criteria to judge the appropriateness of the HSUs selected for use in cost-effectiveness models and is suitable for use in different international settings.

Original language	English
Pages (from-to)	267-275
Number of pages	9
Journal	Value in Health
Volume	22
Issue number	3
DOIs	https://doi.org/10.1016/j.jval.2019.01.004
Publication status	Published - Mar 2019
Externally published	Yes

Keywords

cost effectiveness
economic evaluation
health state utility
preference-based
quality of life
systematic reviews
utilities

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Brazier, J., Ara, R., Azzabi, I., Busschbach, J., Chevrou-Séverac, H., Crawford, B., Cruz, L., Karnon, J., Lloyd, A., Paisley, S., & Pickard, A. S. (2019). Identification, Review, and Use of Health State Utilities in Cost-Effectiveness Models: An ISPOR Good Practices for Outcomes Research Task Force Report. Value in Health, 22(3), 267-275. https://doi.org/10.1016/j.jval.2019.01.004

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abstract = "Cost-effectiveness models that present results in terms of cost per quality-adjusted life-year for health technologies are used to inform policy decisions in many parts of the world. Health state utilities (HSUs) are required to calculate the quality-adjusted life-years. Even when clinical studies assessing the effectiveness of health technologies collect data on HSUs to populate a cost-effectiveness model, which rarely happens, analysts typically need to identify at least some additional HSUs from alternative sources. When possible, HSUs are identified by a systematic review of the literature, but, again, this rarely happens. In 2014, ISPOR established a Good Practices for Outcome Research Task Force to address the use of HSUs in cost-effectiveness models. This task force report provides recommendations for researchers who identify, review, and synthesize HSUs for use in cost-effectiveness models; analysts who use the results in models; and reviewers who critically appraise the suitability and validity of the HSUs selected for use in models. The associated Minimum Reporting Standards of Systematic Review of Utilities for Cost-Effectiveness checklist created by the task force provides criteria to judge the appropriateness of the HSUs selected for use in cost-effectiveness models and is suitable for use in different international settings.",

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Brazier, J, Ara, R, Azzabi, I, Busschbach, J, Chevrou-Séverac, H, Crawford, B, Cruz, L, Karnon, J, Lloyd, A, Paisley, S & Pickard, AS 2019, 'Identification, Review, and Use of Health State Utilities in Cost-Effectiveness Models: An ISPOR Good Practices for Outcomes Research Task Force Report', Value in Health, vol. 22, no. 3, pp. 267-275. https://doi.org/10.1016/j.jval.2019.01.004

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AU - Brazier, John

AU - Ara, Roberta

AU - Azzabi, Ismail

AU - Busschbach, Jan

AU - Chevrou-Séverac, Hélène

AU - Crawford, Bruce

AU - Cruz, Luciane

AU - Karnon, John

AU - Lloyd, Andrew

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Identification, Review, and Use of Health State Utilities in Cost-Effectiveness Models: An ISPOR Good Practices for Outcomes Research Task Force Report

Abstract

Keywords

UN SDGs

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