@article{a517ba24c2434e22808482067382dd1f,
title = "IDH-Mutant Myeloid Neoplasms are Associated with Seronegative Rheumatoid Arthritis and Innate Immune Activation",
abstract = "High prevalence of IDH mutations in seronegative rheumatoid arthritis (RA) with myeloid neoplasm, elevated 2-hydroxyglutarate, dysregulated innate immunity, and proinflammatory microenvironment suggests causative association between IDH mutations and seronegative RA. Our findings merit investigation of IDH inhibitors as therapeutics for seronegative IDH-mutated RA.",
keywords = "MDS, AIRD, t-MN, autoimmune rheumatic diseases",
author = "Hong, {Lih En} and Wechalekar, {Mihir D.} and Monika Kutyna and Annabelle Small and Kelly Lim and Chloe Thompson-Peach and Li, {Joule J.} and Rakchha Chhetri and Scott, {Hamish S.} and Anna Brown and Hahn, {Christopher N.} and Yeung, {David T.} and Salvia Sajid and Nirmal Robinson and Ranjeny Thomas and Susan Branford and D'Andrea, {Richard J.} and Samaraweera, {Saumya E.} and Mrinal Patnaik and Susanna Proudman and Daniel Thomas and Kok, {Chung Hoow} and Shah, {Mithun V.} and Hiwase, {Devendra K.}",
note = "Publisher Copyright: {\textcopyright} 2024 American Society of Hematology",
year = "2024",
month = may,
day = "2",
doi = "10.1182/blood.2023023593",
language = "English",
volume = "143",
pages = "1873--1877",
journal = "Blood",
issn = "0006-4971",
publisher = "Elsevier B.V.",
number = "18",
}