TY - JOUR
T1 - Immunohistochemical detection of cytokines and cell adhesion molecules in the synovial membrane
AU - Parker, Angela
AU - Smith, Malcolm D.
PY - 1999
Y1 - 1999
N2 - This paper describes the immunohistochemical techniques which can be used to detect cytokines and cell adhesion molecules in synovial membrane tissue, including a list of reagents and possible problems in each technique. It also describes three methods of quantitation of the resultant immunohistochemical detection, including the recent innovation computer- assisted digital video image analysis, and lists the advantages and disadvantages of each quantitation technique. This information will be a useful summary for any scientist interested in applying such techniques to the detection of cytokines and cell adhesion molecules in human tissue sections.
AB - This paper describes the immunohistochemical techniques which can be used to detect cytokines and cell adhesion molecules in synovial membrane tissue, including a list of reagents and possible problems in each technique. It also describes three methods of quantitation of the resultant immunohistochemical detection, including the recent innovation computer- assisted digital video image analysis, and lists the advantages and disadvantages of each quantitation technique. This information will be a useful summary for any scientist interested in applying such techniques to the detection of cytokines and cell adhesion molecules in human tissue sections.
KW - Cell adhesion molecules
KW - Cytokines
KW - Immunohistochemistry
KW - Quantitation
UR - http://www.scopus.com/inward/record.url?scp=0033006928&partnerID=8YFLogxK
U2 - 10.1358/mf.1999.21.5.541907
DO - 10.1358/mf.1999.21.5.541907
M3 - Article
C2 - 10420385
AN - SCOPUS:0033006928
VL - 21
SP - 311
EP - 319
JO - Methods and Findings in Experimental and Clinical Pharmacology
JF - Methods and Findings in Experimental and Clinical Pharmacology
SN - 0379-0355
IS - 5
ER -