Impact of Results of a Rapid Staphylococcus aureus Diagnostic Test on prescribing of Antibiotics for Patients with Clustered Gram-Positive Cocci in Blood Cultures

Jane Davies; Claire Gordon; Steven Y. C.  Tong; Robert W. Baird; Joshua S. Davis

doi:10.1128/JCM.06773-11

Impact of Results of a Rapid Staphylococcus aureus Diagnostic Test on prescribing of Antibiotics for Patients with Clustered Gram-Positive Cocci in Blood Cultures

Jane Davies, Claire Gordon, Steven Y. C. Tong, Robert W. Baird, Joshua S. Davis

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

In tropical northern Australia, approximately 20% of Staphylococcus aureus bacteremia is caused by methicillin-resistant Staphylococcus aureus (MRSA). We prospectively evaluated the impact on clinician antibiotic prescribing of the results obtained from performing the GeneXpert MRSA/SA test on 151 positive blood cultures with clustered Gram-positive cocci. The GeneXpert result led to earlier appropriate prescription of vancomycin for 54% of patients with MRSA; 25% of patients avoided vancomycin, and 16% of patients had all antibiotics ceased.

Original language	English
Pages (from-to)	2056-2058
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	50
Issue number	6
DOIs	https://doi.org/10.1128/JCM.06773-11
Publication status	Published - Jun 2012
Externally published	Yes

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AB - In tropical northern Australia, approximately 20% of Staphylococcus aureus bacteremia is caused by methicillin-resistant Staphylococcus aureus (MRSA). We prospectively evaluated the impact on clinician antibiotic prescribing of the results obtained from performing the GeneXpert MRSA/SA test on 151 positive blood cultures with clustered Gram-positive cocci. The GeneXpert result led to earlier appropriate prescription of vancomycin for 54% of patients with MRSA; 25% of patients avoided vancomycin, and 16% of patients had all antibiotics ceased.

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Impact of Results of a Rapid Staphylococcus aureus Diagnostic Test on prescribing of Antibiotics for Patients with Clustered Gram-Positive Cocci in Blood Cultures

Abstract

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