In vitro approaches can predict human drug metabolism

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

Classical approaches to characterizing the pharmacokinetics, metabolism and interactions of new drugs have involved animal studies to define potential metabolic pathways, phase I studies in humans that often use the radio-labelled compound to define actual pathways, and drug interaction studies in volunteer subjects and patients.
Original languageEnglish
Pages (from-to)292-294
Number of pages3
JournalTrends in Pharmacological Sciences
Volume14
Issue number8
DOIs
Publication statusPublished - Aug 1993
Externally publishedYes

Keywords

  • in vitro
  • metabolism
  • drugs

Fingerprint Dive into the research topics of 'In vitro approaches can predict human drug metabolism'. Together they form a unique fingerprint.

  • Cite this