Incidence and Prevalence of Keratoconus Based on Scheimpflug Imaging

Elsie Chan, Elaine W. Chong, Samantha Sze Yee Lee, Maria Franchina, Seyhan Yazar, Peter Eastwood, Nigel McArdle, David A. Mackey, Gareth Lingham

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Keratoconus is a disorder characterized by bilateral corneal thinning, with an onset typically in the first 3 decades of life. In this study, we report the prevalence of keratoconus among 28-year-old Generation 2 (Gen2) participants of the Raine Study in Western Australia, the incidence between 20 and 28 years of age, and the risk factors associated with keratoconus.

We have previously reported the prevalence of keratoconus at the 20-year follow-up of the Raine Study as 1.2% or 120 cases per 100 000 people. Previous publications based on national health insurance data include a reported keratoconus prevalence of 265 cases per 100 000 and an annual incidence of 13.3 cases per 100 000 in The Netherlands. However, health insurance databases likely underestimate true disease prevalence and incidence...
Original languageEnglish
Pages (from-to)445-448
Number of pages4
Issue number4
Early online date2 Dec 2022
Publication statusPublished - Apr 2023


  • Cohort study
  • Cornea
  • Epidemiology
  • Keratoconus
  • Scheimpflug imaging


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