Incidence and Prevalence of Keratoconus Based on Scheimpflug Imaging

Elsie Chan; Elaine W. Chong; Samantha Sze Yee Lee; Maria Franchina; Seyhan Yazar; Peter Eastwood; Nigel McArdle; David A. Mackey; Gareth Lingham

doi:10.1016/j.ophtha.2022.11.027

Incidence and Prevalence of Keratoconus Based on Scheimpflug Imaging

Elsie Chan, Elaine W. Chong, Samantha Sze Yee Lee, Maria Franchina, Seyhan Yazar, Peter Eastwood, Nigel McArdle, David A. Mackey, Gareth Lingham

College of Medicine and Public Health

Research output: Contribution to journal › Article › peer-review

2 Downloads (Pure)

Abstract

Keratoconus is a disorder characterized by bilateral corneal thinning, with an onset typically in the first 3 decades of life. In this study, we report the prevalence of keratoconus among 28-year-old Generation 2 (Gen2) participants of the Raine Study in Western Australia, the incidence between 20 and 28 years of age, and the risk factors associated with keratoconus.

We have previously reported the prevalence of keratoconus at the 20-year follow-up of the Raine Study as 1.2% or 120 cases per 100 000 people. Previous publications based on national health insurance data include a reported keratoconus prevalence of 265 cases per 100 000 and an annual incidence of 13.3 cases per 100 000 in The Netherlands. However, health insurance databases likely underestimate true disease prevalence and incidence...

Original language	English
Pages (from-to)	445-448
Number of pages	4
Journal	Ophthalmology
Volume	130
Issue number	4
Early online date	2 Dec 2022
DOIs	https://doi.org/10.1016/j.ophtha.2022.11.027
Publication status	Published - Apr 2023

Keywords

Cohort study
Cornea
Epidemiology
Keratoconus
Scheimpflug imaging

Access to Document

10.1016/j.ophtha.2022.11.027Licence: CC BY-NC-ND

1-s2.0-S0161642022009332-main (1)Final published version, 437 KBLicence: CC BY-NC-ND

Cite this

@article{0efdfb7473cf41cb890e47b4edc6219e,

title = "Incidence and Prevalence of Keratoconus Based on Scheimpflug Imaging",

abstract = "Keratoconus is a disorder characterized by bilateral corneal thinning, with an onset typically in the first 3 decades of life. In this study, we report the prevalence of keratoconus among 28-year-old Generation 2 (Gen2) participants of the Raine Study in Western Australia, the incidence between 20 and 28 years of age, and the risk factors associated with keratoconus.We have previously reported the prevalence of keratoconus at the 20-year follow-up of the Raine Study as 1.2% or 120 cases per 100 000 people. Previous publications based on national health insurance data include a reported keratoconus prevalence of 265 cases per 100 000 and an annual incidence of 13.3 cases per 100 000 in The Netherlands. However, health insurance databases likely underestimate true disease prevalence and incidence...",

keywords = "Cohort study, Cornea, Epidemiology, Keratoconus, Scheimpflug imaging",

author = "Elsie Chan and Chong, {Elaine W.} and Lee, {Samantha Sze Yee} and Maria Franchina and Seyhan Yazar and Peter Eastwood and Nigel McArdle and Mackey, {David A.} and Gareth Lingham",

year = "2023",

month = apr,

doi = "10.1016/j.ophtha.2022.11.027",

language = "English",

volume = "130",

pages = "445--448",

journal = "Ophthalmology",

issn = "0161-6420",

publisher = "Elsevier Inc.",

number = "4",

}

TY - JOUR

T1 - Incidence and Prevalence of Keratoconus Based on Scheimpflug Imaging

AU - Chan, Elsie

AU - Chong, Elaine W.

AU - Lee, Samantha Sze Yee

AU - Franchina, Maria

AU - Yazar, Seyhan

AU - Eastwood, Peter

AU - McArdle, Nigel

AU - Mackey, David A.

AU - Lingham, Gareth

PY - 2023/4

Y1 - 2023/4

N2 - Keratoconus is a disorder characterized by bilateral corneal thinning, with an onset typically in the first 3 decades of life. In this study, we report the prevalence of keratoconus among 28-year-old Generation 2 (Gen2) participants of the Raine Study in Western Australia, the incidence between 20 and 28 years of age, and the risk factors associated with keratoconus.We have previously reported the prevalence of keratoconus at the 20-year follow-up of the Raine Study as 1.2% or 120 cases per 100 000 people. Previous publications based on national health insurance data include a reported keratoconus prevalence of 265 cases per 100 000 and an annual incidence of 13.3 cases per 100 000 in The Netherlands. However, health insurance databases likely underestimate true disease prevalence and incidence...

AB - Keratoconus is a disorder characterized by bilateral corneal thinning, with an onset typically in the first 3 decades of life. In this study, we report the prevalence of keratoconus among 28-year-old Generation 2 (Gen2) participants of the Raine Study in Western Australia, the incidence between 20 and 28 years of age, and the risk factors associated with keratoconus.We have previously reported the prevalence of keratoconus at the 20-year follow-up of the Raine Study as 1.2% or 120 cases per 100 000 people. Previous publications based on national health insurance data include a reported keratoconus prevalence of 265 cases per 100 000 and an annual incidence of 13.3 cases per 100 000 in The Netherlands. However, health insurance databases likely underestimate true disease prevalence and incidence...

KW - Cohort study

KW - Cornea

KW - Epidemiology

KW - Keratoconus

KW - Scheimpflug imaging

UR - http://www.scopus.com/inward/record.url?scp=85146475946&partnerID=8YFLogxK

UR - http://purl.org/au-research/grants/NHMRC/1021105

UR - http://purl.org/au-research/grants/NHMRC/1022134

UR - http://purl.org/au-research/grants/NHMRC/1027449

UR - http://purl.org/au-research/grants/NHMRC/1121979

UR - http://purl.org/au-research/grants/NHMRC/1126494

U2 - 10.1016/j.ophtha.2022.11.027

DO - 10.1016/j.ophtha.2022.11.027

M3 - Article

C2 - 36464154

AN - SCOPUS:85146475946

SN - 0161-6420

VL - 130

SP - 445

EP - 448

JO - Ophthalmology

JF - Ophthalmology

IS - 4

ER -

Incidence and Prevalence of Keratoconus Based on Scheimpflug Imaging

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this