Increased abundance of Sutterella spp. and Ruminococcus torques in feces of children with autism spectrum disorder

Lv Wang, Claus Christophersen, Michael Sorich, Jacobas Gerber, Manya Angley, Michael Conlon

    Research output: Contribution to journalArticle

    156 Citations (Scopus)

    Abstract

    Background: A recent report indicated that numbers of Sutterella spp. are elevated in gastrointestinal biopsies taken from children with autism spectrum disorder (ASD). We have recently reported changes in the numbers of some bacteria within the stool of ASD children, and now examine whether numbers of Sutterella spp. and some other mucosa-associated bacteria linked with gastrointestinal disease (Ruminococcus gnavus and Ruminococcus torques) are also altered in the stool of these children. Findings. We show that numbers of Sutterella spp. are elevated in feces of ASD children relative to controls, and that numbers of R. torques are higher in the children with ASD with a reported functional gastrointestinal disorder than those without such a disorder. Conclusions: We show further evidence of changes in the gut microbiota of children with ASD and confirm that the abundance of Sutterella spp. is altered in stool.

    Original languageEnglish
    Article number42
    Pages (from-to)1-4
    Number of pages4
    JournalMolecular Autism
    Volume4
    Issue number42
    DOIs
    Publication statusPublished - 2013

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