Increased BMI ‘alone’ does not negatively influence sperm function - a retrospective analysis of men attending fertility treatment with corresponding liver function results

Nicole O. McPherson; Kelton Tremellen

doi:10.1016/j.orcp.2020.03.003

Increased BMI ‘alone’ does not negatively influence sperm function - a retrospective analysis of men attending fertility treatment with corresponding liver function results

Nicole O. McPherson, Kelton Tremellen

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Does increased body mass index (BMI) without an underlying metabolic issue negatively influence semen quality? Proof of concept we conducted retrospective data analysis of men (N = 84) undergoing assisted reproductive technology, who had liver function testing with fasted glucose concentrations and corresponding hormone profile (testosterone, LH, FSH and prolactin) and semen analysis. Sperm count and total concentration were only reduced in metabolically unhealthy overweight/obese men. Serum GTT was the biggest predictor of Normozoospermia and Oligospermia, with BMI having no effect. Increased BMI without an underlying metabolic condition (in particular signs of NAFLD) has no influence on semen quality.

Original language	English
Pages (from-to)	164-167
Number of pages	4
Journal	Obesity Research and Clinical Practice
Volume	14
Issue number	2
DOIs	https://doi.org/10.1016/j.orcp.2020.03.003
Publication status	Published - Mar 2020

Keywords

Infertility
Metabolic syndrome
Obesity
Semen

Access to Document

10.1016/j.orcp.2020.03.003Licence: In Copyright

Cite this

@article{a1791fb5cf1d4191a18aac298be4a884,

title = "Increased BMI {\textquoteleft}alone{\textquoteright} does not negatively influence sperm function - a retrospective analysis of men attending fertility treatment with corresponding liver function results",

abstract = "Does increased body mass index (BMI) without an underlying metabolic issue negatively influence semen quality? Proof of concept we conducted retrospective data analysis of men (N = 84) undergoing assisted reproductive technology, who had liver function testing with fasted glucose concentrations and corresponding hormone profile (testosterone, LH, FSH and prolactin) and semen analysis. Sperm count and total concentration were only reduced in metabolically unhealthy overweight/obese men. Serum GTT was the biggest predictor of Normozoospermia and Oligospermia, with BMI having no effect. Increased BMI without an underlying metabolic condition (in particular signs of NAFLD) has no influence on semen quality.",

keywords = "Infertility, Metabolic syndrome, Obesity, Semen",

author = "McPherson, {Nicole O.} and Kelton Tremellen",

year = "2020",

month = mar,

doi = "10.1016/j.orcp.2020.03.003",

language = "English",

volume = "14",

pages = "164--167",

journal = "Obesity Research and Clinical Practice",

issn = "1871-403X",

number = "2",

}

TY - JOUR

T1 - Increased BMI ‘alone’ does not negatively influence sperm function - a retrospective analysis of men attending fertility treatment with corresponding liver function results

AU - McPherson, Nicole O.

AU - Tremellen, Kelton

PY - 2020/3

Y1 - 2020/3

N2 - Does increased body mass index (BMI) without an underlying metabolic issue negatively influence semen quality? Proof of concept we conducted retrospective data analysis of men (N = 84) undergoing assisted reproductive technology, who had liver function testing with fasted glucose concentrations and corresponding hormone profile (testosterone, LH, FSH and prolactin) and semen analysis. Sperm count and total concentration were only reduced in metabolically unhealthy overweight/obese men. Serum GTT was the biggest predictor of Normozoospermia and Oligospermia, with BMI having no effect. Increased BMI without an underlying metabolic condition (in particular signs of NAFLD) has no influence on semen quality.

AB - Does increased body mass index (BMI) without an underlying metabolic issue negatively influence semen quality? Proof of concept we conducted retrospective data analysis of men (N = 84) undergoing assisted reproductive technology, who had liver function testing with fasted glucose concentrations and corresponding hormone profile (testosterone, LH, FSH and prolactin) and semen analysis. Sperm count and total concentration were only reduced in metabolically unhealthy overweight/obese men. Serum GTT was the biggest predictor of Normozoospermia and Oligospermia, with BMI having no effect. Increased BMI without an underlying metabolic condition (in particular signs of NAFLD) has no influence on semen quality.

KW - Infertility

KW - Metabolic syndrome

KW - Obesity

KW - Semen

UR - http://www.scopus.com/inward/record.url?scp=85083313302&partnerID=8YFLogxK

UR - http://purl.org/au-research/grants/NHMRC/1088964

U2 - 10.1016/j.orcp.2020.03.003

DO - 10.1016/j.orcp.2020.03.003

M3 - Article

C2 - 32321679

AN - SCOPUS:85083313302

VL - 14

SP - 164

EP - 167

JO - Obesity Research and Clinical Practice

JF - Obesity Research and Clinical Practice

SN - 1871-403X

IS - 2

ER -

Increased BMI ‘alone’ does not negatively influence sperm function - a retrospective analysis of men attending fertility treatment with corresponding liver function results

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this