Increasing Prevalence of Untypable and Mixed Genotypes of Hepatitis C Virus in Pakistan: Latest Trends in 2018

Braira Wahid; Nabiha Naeem; Saba Altaf; Nimra Ilyas

doi:10.1089/vim.2018.0152

Increasing Prevalence of Untypable and Mixed Genotypes of Hepatitis C Virus in Pakistan: Latest Trends in 2018

Braira Wahid, Nabiha Naeem, Saba Altaf, Nimra Ilyas

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Hepatitis C virus (HCV) genotyping is a critical parameter that acts as predictor of treatment response. According to previously reported findings, about 11 million population of Pakistan are HCV infected. Accumulating data suggest that genotype is the most prevalent genotype and mixed and untypable genotypes are the least prevalent genotypes of HCV. We observed that overall prevalence of mixed genotype (5.03%) and untypable genotype (3.3%) of HCV is on constant rise. This study highlights that the emergence of novel quasispecies could be reason of treatment failure in patients receiving direct-acting antiviral drugs.

Original language	English
Pages (from-to)	192-194
Number of pages	3
Journal	Viral Immunology
Volume	32
Issue number	4
DOIs	https://doi.org/10.1089/vim.2018.0152
Publication status	Published - May 2019
Externally published	Yes

Keywords

Genome Centre for Molecular Based Diagnostics and Research (GCMBDR)
genotyping
HCV
Pakistan

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1089/vim.2018.0152Licence: In Copyright

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AU - Altaf, Saba

AU - Ilyas, Nimra

PY - 2019/5

Y1 - 2019/5

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AB - Hepatitis C virus (HCV) genotyping is a critical parameter that acts as predictor of treatment response. According to previously reported findings, about 11 million population of Pakistan are HCV infected. Accumulating data suggest that genotype is the most prevalent genotype and mixed and untypable genotypes are the least prevalent genotypes of HCV. We observed that overall prevalence of mixed genotype (5.03%) and untypable genotype (3.3%) of HCV is on constant rise. This study highlights that the emergence of novel quasispecies could be reason of treatment failure in patients receiving direct-acting antiviral drugs.

KW - Genome Centre for Molecular Based Diagnostics and Research (GCMBDR)

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ER -

Increasing Prevalence of Untypable and Mixed Genotypes of Hepatitis C Virus in Pakistan: Latest Trends in 2018

Abstract

Keywords

UN SDGs

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