Increasing Use of Antenatal Magnesium Sulphate Prior to Preterm Birth for Preventing Cerebral Palsy in Australia and New Zealand, 2012–2020: A Binational Registry Study

Emily Shepherd; Sarah McIntyre; Alice Rumbold; Tasneem Karim; Shona Goldsmith; Amy Keir; Amanda Poprzeczny; Rod W. Hunt; Nadia Badawi; Christopher J.D. Mckinlay; Caroline A. Crowther; Lisa Yelland; the Australian and New Zealand Neonatal Network (ANZNN)

doi:10.1111/ajo.13937

Increasing Use of Antenatal Magnesium Sulphate Prior to Preterm Birth for Preventing Cerebral Palsy in Australia and New Zealand, 2012–2020: A Binational Registry Study

Emily Shepherd, Sarah McIntyre, Alice Rumbold, Tasneem Karim, Shona Goldsmith, Amy Keir, Amanda Poprzeczny, Rod W. Hunt, Nadia Badawi, Christopher J.D. Mckinlay, Caroline A. Crowther, Lisa Yelland, the Australian and New Zealand Neonatal Network (ANZNN)

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Abstract

We assessed the use of magnesium sulphate prior to preterm birth for preventing cerebral palsy in an Australian and New Zealand registry study. Use increased markedly from 32.3% (2012) to 78.8% (2020) (p < 0.001). Binational approaches to sustain and explore the feasibility of further increasing use, informed by evolving evidence and guidelines, are needed.

Original language	English
Number of pages	5
Journal	Australian and New Zealand Journal of Obstetrics and Gynaecology
DOIs	https://doi.org/10.1111/ajo.13937
Publication status	E-pub ahead of print - 16 Jan 2025
Externally published	Yes

Keywords

cerebral palsy
guideline adherence
infant
magnesium sulphate
premature
premature birth

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10.1111/ajo.13937Licence: CC BY

Final published versionFinal published version, 379 KBLicence: CC BY

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Shepherd, E., McIntyre, S., Rumbold, A., Karim, T., Goldsmith, S., Keir, A., Poprzeczny, A., Hunt, R. W., Badawi, N., Mckinlay, C. J. D., Crowther, C. A., Yelland, L., & the Australian and New Zealand Neonatal Network (ANZNN) (2025). Increasing Use of Antenatal Magnesium Sulphate Prior to Preterm Birth for Preventing Cerebral Palsy in Australia and New Zealand, 2012–2020: A Binational Registry Study. Australian and New Zealand Journal of Obstetrics and Gynaecology. Advance online publication. https://doi.org/10.1111/ajo.13937

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abstract = "We assessed the use of magnesium sulphate prior to preterm birth for preventing cerebral palsy in an Australian and New Zealand registry study. Use increased markedly from 32.3% (2012) to 78.8% (2020) (p < 0.001). Binational approaches to sustain and explore the feasibility of further increasing use, informed by evolving evidence and guidelines, are needed.",

keywords = "cerebral palsy, guideline adherence, infant, magnesium sulphate, premature, premature birth",

author = "Emily Shepherd and Sarah McIntyre and Alice Rumbold and Tasneem Karim and Shona Goldsmith and Amy Keir and Amanda Poprzeczny and Hunt, {Rod W.} and Nadia Badawi and Mckinlay, {Christopher J.D.} and Crowther, {Caroline A.} and Lisa Yelland and {the Australian and New Zealand Neonatal Network (ANZNN)}",

year = "2025",

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doi = "10.1111/ajo.13937",

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journal = "Australian and New Zealand Journal of Obstetrics and Gynaecology",

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Shepherd, E, McIntyre, S, Rumbold, A, Karim, T, Goldsmith, S, Keir, A, Poprzeczny, A, Hunt, RW, Badawi, N, Mckinlay, CJD, Crowther, CA, Yelland, L & the Australian and New Zealand Neonatal Network (ANZNN) 2025, 'Increasing Use of Antenatal Magnesium Sulphate Prior to Preterm Birth for Preventing Cerebral Palsy in Australia and New Zealand, 2012–2020: A Binational Registry Study', Australian and New Zealand Journal of Obstetrics and Gynaecology. https://doi.org/10.1111/ajo.13937

Increasing Use of Antenatal Magnesium Sulphate Prior to Preterm Birth for Preventing Cerebral Palsy in Australia and New Zealand, 2012–2020: A Binational Registry Study. / Shepherd, Emily; McIntyre, Sarah; Rumbold, Alice et al.
In: Australian and New Zealand Journal of Obstetrics and Gynaecology, 16.01.2025.

Research output: Contribution to journal › Article › peer-review

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AU - Shepherd, Emily

AU - McIntyre, Sarah

AU - Rumbold, Alice

AU - Karim, Tasneem

AU - Goldsmith, Shona

AU - Keir, Amy

AU - Poprzeczny, Amanda

AU - Hunt, Rod W.

AU - Badawi, Nadia

AU - Mckinlay, Christopher J.D.

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AU - Yelland, Lisa

AU - the Australian and New Zealand Neonatal Network (ANZNN)

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KW - premature birth

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ER -

Increasing Use of Antenatal Magnesium Sulphate Prior to Preterm Birth for Preventing Cerebral Palsy in Australia and New Zealand, 2012–2020: A Binational Registry Study

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