Inhibition of glycollate metabolism by amino-oxyacetate: Consequences for photosynthesis

C. L.D. Jenkins, L. J. Rogers, M. W. Kerr

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)


The potential of amino-oxyacetate as an inhibitor of photorespiratory metabolism has been assessed. In the presence of inhibitor at 10μM, assimilation of 14CO2 in Hordeum vulgare was decreased by 72%, and in Zea mays by 42%; for amino-oxyacetate at 100μM the corresponding inhibitions were 90% and 72%, respectively. Labelling patterns showed reduced incorporation into most metabolites, that into sucrose being notably depressed. As a percentage of total incorporation hexose monophosphate, glycollate and serine concentrations were increased following inhibitor treatment. The increased incorporation into glycollate was particularly evident in maize, where a marked increase in net assimilation into this compound was observed. Enzymic studies on plant extracts treated in vitro with amino-oxyacetate suggested that serine:glyoxylate aminotransferase was the primary site of inhibition, and glutamate:glyoxylate aminotransferase and particularly serine hydroxymethyltransferase were appreciably less sensitive to inhibition.

Original languageEnglish
Pages (from-to)19-23
Number of pages5
Issue number1
Publication statusPublished - 1983
Externally publishedYes


  • amino-oxyacetate
  • barley
  • Gramineae
  • Hordeum vulgare
  • maize
  • photorespiration
  • photosynthesis
  • pyridoxal 5′-phosphate.
  • Zea mays


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