TY - JOUR
T1 - Inorganic-organic hybrid materials to detect urinary biomarkers
T2 - recent progress and future prospects
AU - Hu, Qi
AU - Ding, Dan
AU - Tang, Youhong
PY - 2022/8/7
Y1 - 2022/8/7
N2 - Inorganic-organic hybrid materials have received extensive attention due to their excellent properties of recombination. In the framework of biological and chemical sensing, the utilization of hybrid materials for disease monitoring and diagnosis is a detection method worthy of current investigation. Biomarkers linked to urinary diseases play critical roles in the screening and identification of disease during this process. To date, a variety of hybrid biosensors have been synthesized for the detection of biomarkers in human urine. In this review, the present state of hybrid materials research for the sensing of biomarkers in urine is summarized; meanwhile, the physiological significance of urine biomarkers and the problems that still exist with the detection system are expounded. Consequently, strategies, such as using rotating systems, are provided for future researchers to optimize the design, synthesis, and experimental methods of hybrid materials to achieve suitable performance in urine biomarker detection.
AB - Inorganic-organic hybrid materials have received extensive attention due to their excellent properties of recombination. In the framework of biological and chemical sensing, the utilization of hybrid materials for disease monitoring and diagnosis is a detection method worthy of current investigation. Biomarkers linked to urinary diseases play critical roles in the screening and identification of disease during this process. To date, a variety of hybrid biosensors have been synthesized for the detection of biomarkers in human urine. In this review, the present state of hybrid materials research for the sensing of biomarkers in urine is summarized; meanwhile, the physiological significance of urine biomarkers and the problems that still exist with the detection system are expounded. Consequently, strategies, such as using rotating systems, are provided for future researchers to optimize the design, synthesis, and experimental methods of hybrid materials to achieve suitable performance in urine biomarker detection.
KW - detection of urinary biomarkers
KW - inorganic–organic hybrid materials
KW - recombination
UR - http://www.scopus.com/inward/record.url?scp=85131764703&partnerID=8YFLogxK
U2 - 10.1039/d2qm00213b
DO - 10.1039/d2qm00213b
M3 - Review article
AN - SCOPUS:85131764703
SN - 2052-1537
VL - 6
SP - 2011
EP - 2033
JO - Materials Chemistry Frontiers
JF - Materials Chemistry Frontiers
IS - 15
ER -