OSA is a highly prevalent, chronic condition that is frequently associated with modifiable risk factors and multiple medical comorbidities. Effective management of OSA requires a comprehensive, multidisciplinary, patient-centred approach that addresses not only the sleep disordered breathing events but also includes evaluation for and treatment of related medical comorbidities and strategies to optimise treatment adherence. Integrated care for OSA involves collaboration between health professionals from a variety of disciplines. There is significant potential for specialist nurses, as well as primary care physicians, to take greater responsibility for the diagnosis and management of OSA. Strategies aimed at promoting patient self-management and improving communication between patients and healthcare providers, including structured chronic disease self-management programmes and use of e-health interventions and related technologies, may be of benefit for patients with OSA.