TY - JOUR
T1 - Integration of genomic and proteomic analyses in the classification of the Siphoviridae family
AU - Adriaenssens, Evelien M.
AU - Edwards, Rob
AU - Nash, John H.E.
AU - Mahadevan, Padmanabhan
AU - Seto, Donald
AU - Ackermann, Hans Wolfgang
AU - Lavigne, Rob
AU - Kropinski, Andrew M.
PY - 2015/3
Y1 - 2015/3
N2 - Using a variety of genomic (BLASTN, ClustalW) and proteomic (Phage Proteomic Tree, CoreGenes) tools we have tackled the taxonomic status of members of the largest bacteriophage family, the Siphoviridae. In all over 400 phages were examined and we were able to propose 39 new genera, comprising 216 phage species, and add 62 species to two previously defined genera (. Phic3unalikevirus; L5likevirus) grouping, in total, 390 fully sequenced phage isolates. Many of the remainders are orphans which the Bacterial and Archaeal Viruses Subcommittee of the International Committee on Taxonomy of Viruses (ICTV) chooses not to ascribe genus status at the time being.
AB - Using a variety of genomic (BLASTN, ClustalW) and proteomic (Phage Proteomic Tree, CoreGenes) tools we have tackled the taxonomic status of members of the largest bacteriophage family, the Siphoviridae. In all over 400 phages were examined and we were able to propose 39 new genera, comprising 216 phage species, and add 62 species to two previously defined genera (. Phic3unalikevirus; L5likevirus) grouping, in total, 390 fully sequenced phage isolates. Many of the remainders are orphans which the Bacterial and Archaeal Viruses Subcommittee of the International Committee on Taxonomy of Viruses (ICTV) chooses not to ascribe genus status at the time being.
KW - ClustalW
KW - CoreGenes
KW - ICTV
KW - Phage Proteomic Tree
KW - Siphoviridae
KW - Taxonomy
UR - http://www.scopus.com/inward/record.url?scp=84929999962&partnerID=8YFLogxK
U2 - 10.1016/j.virol.2014.10.016
DO - 10.1016/j.virol.2014.10.016
M3 - Article
C2 - 25466308
AN - SCOPUS:84929999962
VL - 477
SP - 144
EP - 154
JO - Virology
JF - Virology
SN - 0042-6822
ER -