Interaction of Campylobacter pyloridis with human immune defence mechanisms

H. Pruul, P. C. Lee, C. S. Goodwin, P. J. McDonald

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The in-vitro susceptibility to host immune defence mechanisms of Campylobacter pyloridis was investigated. C. pyloridis was sensitive to antibody-dependent complement-mediated bactericidal activity of serum. The bacteria were phagocytosed and efficiently killed by polymorphonuclear neutrophils in the presence of serum opsonins. Serum opsonin depletion studies indicated that an intact classical complement pathway was required for optimal phagocytic killing.

Original languageEnglish
Pages (from-to)233-238
Number of pages6
JournalJournal of Medical Microbiology
Volume23
Issue number3
DOIs
Publication statusPublished - 1 May 1987
Externally publishedYes

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