Interactive pharmacometric applications using R and the Shiny package

Jessica Wojciechowski; Ashley M. Hopkins; Richard Neil Upton

doi:10.1002/psp4.21

Interactive pharmacometric applications using R and the Shiny package

Jessica Wojciechowski, Ashley M. Hopkins, Richard Neil Upton

Flinders University

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

53 Downloads (Pure)

Abstract

Interactive applications, developed using Shiny for the R programming language, have the potential to revolutionize the sharing and communication of pharmacometric model simulations. Shiny allows customization of the application's user-interface to provide an elegant environment for displaying user-input controls and simulation output-where the latter simultaneously updates with changing input. The flexible nature of the R language makes simulations of population variability possible thus promoting the combination of Shiny with R in model visualization.

Original language	English
Pages (from-to)	146-159
Number of pages	14
Journal	CPT: Pharmacometrics and Systems Pharmacology
Volume	4
Issue number	3
DOIs	https://doi.org/10.1002/psp4.21
Publication status	Published - Mar 2015

Bibliographical note

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

Keywords

pharmacometric model applications
population variability

Access to Document

10.1002/psp4.21Licence: CC BY-NC

Wojciechowski_Interactive_P2015Final published version, 643 KBLicence: CC BY-NC

Fingerprint Dive into the research topics of 'Interactive pharmacometric applications using R and the Shiny package'. Together they form a unique fingerprint.

Cite this

@article{d23e611fadee4116a5c7ac9e765df75e,

title = "Interactive pharmacometric applications using R and the Shiny package",

abstract = "Interactive applications, developed using Shiny for the R programming language, have the potential to revolutionize the sharing and communication of pharmacometric model simulations. Shiny allows customization of the application's user-interface to provide an elegant environment for displaying user-input controls and simulation output-where the latter simultaneously updates with changing input. The flexible nature of the R language makes simulations of population variability possible thus promoting the combination of Shiny with R in model visualization.",

keywords = "pharmacometric model applications, population variability",

author = "Jessica Wojciechowski and Hopkins, {Ashley M.} and Upton, {Richard Neil}",

note = "This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.",

year = "2015",

month = mar,

doi = "10.1002/psp4.21",

language = "English",

volume = "4",

pages = "146--159",

journal = "CPT: Pharmacometrics and Systems Pharmacology",

issn = "2163-8306",

publisher = "Nature Publishing Group",

number = "3",

}

TY - JOUR

T1 - Interactive pharmacometric applications using R and the Shiny package

AU - Wojciechowski, Jessica

AU - Hopkins, Ashley M.

AU - Upton, Richard Neil

N1 - This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

PY - 2015/3

Y1 - 2015/3

N2 - Interactive applications, developed using Shiny for the R programming language, have the potential to revolutionize the sharing and communication of pharmacometric model simulations. Shiny allows customization of the application's user-interface to provide an elegant environment for displaying user-input controls and simulation output-where the latter simultaneously updates with changing input. The flexible nature of the R language makes simulations of population variability possible thus promoting the combination of Shiny with R in model visualization.

AB - Interactive applications, developed using Shiny for the R programming language, have the potential to revolutionize the sharing and communication of pharmacometric model simulations. Shiny allows customization of the application's user-interface to provide an elegant environment for displaying user-input controls and simulation output-where the latter simultaneously updates with changing input. The flexible nature of the R language makes simulations of population variability possible thus promoting the combination of Shiny with R in model visualization.

KW - pharmacometric model applications

KW - population variability

U2 - 10.1002/psp4.21

DO - 10.1002/psp4.21

M3 - Article

VL - 4

SP - 146

EP - 159

JO - CPT: Pharmacometrics and Systems Pharmacology

JF - CPT: Pharmacometrics and Systems Pharmacology

SN - 2163-8306

IS - 3

ER -