Interactive pharmacometric applications using R and the Shiny package

Jessica Wojciechowski, Ashley M. Hopkins, Richard Neil Upton

Research output: Contribution to journalReview articlepeer-review

34 Citations (Scopus)
70 Downloads (Pure)


Interactive applications, developed using Shiny for the R programming language, have the potential to revolutionize the sharing and communication of pharmacometric model simulations. Shiny allows customization of the application's user-interface to provide an elegant environment for displaying user-input controls and simulation output-where the latter simultaneously updates with changing input. The flexible nature of the R language makes simulations of population variability possible thus promoting the combination of Shiny with R in model visualization.

Original languageEnglish
Pages (from-to)146-159
Number of pages14
JournalCPT: Pharmacometrics and Systems Pharmacology
Issue number3
Publication statusPublished - Mar 2015

Bibliographical note

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.


  • pharmacometric model applications
  • population variability

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