Intracellular free calcium and inositol polyphosphate action as potential targets in the ageing process

Gregory J. Barritt

doi:10.1016/0197-4580(87)90079-0

Intracellular free calcium and inositol polyphosphate action as potential targets in the ageing process

Gregory J. Barritt

Research output: Contribution to journal › Comment/debate

12 Citations (Scopus)

Abstract

The concentration of free Ca²⁺ in the cell cytoplasm is likely to be the most important parameter which should be considered in assessing the contribution of Ca²⁺ to regulation of neurotransmitter release, memory development and cell growth. Quantitative measurement of the free Ca²⁺ concentration and elucidation of the membrane transduction systems which control this parameter in aged neuronal cells may make a significant contribution to further define the role of Ca²⁺ in the ageing nervous system.

Original language	English
Pages (from-to)	357-359
Number of pages	3
Journal	Neurobiology of Aging
Volume	8
Issue number	4
DOIs	https://doi.org/10.1016/0197-4580(87)90079-0
Publication status	Published - Aug 1987

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title = "Intracellular free calcium and inositol polyphosphate action as potential targets in the ageing process",

abstract = "The concentration of free Ca2+ in the cell cytoplasm is likely to be the most important parameter which should be considered in assessing the contribution of Ca2+ to regulation of neurotransmitter release, memory development and cell growth. Quantitative measurement of the free Ca2+ concentration and elucidation of the membrane transduction systems which control this parameter in aged neuronal cells may make a significant contribution to further define the role of Ca2+ in the ageing nervous system.",

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AB - The concentration of free Ca2+ in the cell cytoplasm is likely to be the most important parameter which should be considered in assessing the contribution of Ca2+ to regulation of neurotransmitter release, memory development and cell growth. Quantitative measurement of the free Ca2+ concentration and elucidation of the membrane transduction systems which control this parameter in aged neuronal cells may make a significant contribution to further define the role of Ca2+ in the ageing nervous system.

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U2 - 10.1016/0197-4580(87)90079-0

DO - 10.1016/0197-4580(87)90079-0

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JO - Neurobiology of Aging

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ER -

Intracellular free calcium and inositol polyphosphate action as potential targets in the ageing process

Abstract

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