Intramolecular motion-associated biomaterials (iMAB) are developing rapidly in the field of image-guided cancer surgery by virtue of their easily regulated photophysical property. Through manipulating the energy distribution after absorption of light, we can easily control the maximal energy decay of iMAB through radiative pathway or non-radiative pathway for optimized fluorescence guidance or promoted photoacoustic imaging guidance. Therefore, iMAB provide an opportunity to utilize the maximum potential of imaging reagents for precise guidance of cancer surgery. In this short review, recent progress in this field has been summarized and discussed to illuminate the design and regulation principles of iMAB for advanced precise cancer surgery.
|Number of pages||8|
|Journal||Smart Materials in Medicine|
|Publication status||Published - Jan 2020|
- Imaging guidance
- Intermolecular interactions
- Intramolecular motions
- Photophysical property