Investigating the structural and thermodynamic basis of substrate selectivities of human cytochrome P450 enzymes: A Molecular Dynamics study

Research output: Contribution to conferenceAbstract

Abstract

Enzymes of the cytochrome P450 (CYP) superfamily are responsible for the metabolism of a myriad of compounds that include drugs, non-drug xenobiotics (e.g. environmental chemicals), and endogenous compounds. The individual P450 enzymes exhibit characteristic substrate and inhibitor selectivities, and enzyme activities are variably affected by age, ...
Original languageEnglish
Publication statusPublished - 2014
Event5th FIP Pharmaceutical Sciences World Congress -
Duration: 13 Apr 2014 → …

Conference

Conference5th FIP Pharmaceutical Sciences World Congress
Period13/04/14 → …

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