Investigation of medication adherence and reasons for poor adherence in patients on long-term glaucoma treatment regimes

Julie McClelland, Lynne Bodle, Julie-Anne Little

    Research output: Contribution to journalArticlepeer-review

    4 Citations (Scopus)
    9 Downloads (Pure)

    Abstract

    PURPOSE:
    Long-term treatment adherence for a chronic asymptomatic condition is a demanding task for many patients. Treating progressive glaucoma can also be confounding for physicians, particularly when management relies on assumption of adherence. This study investigated associations between self-reported adherence and frequency of medication changes due to glaucoma progression.
    METHODS:
    A total of 128 participants with primary open angle glaucoma were recruited from glaucoma clinics in Flinders Eye Center, South Australia, and completed confidential questionnaires. Information was obtained regarding beliefs about glaucoma and their treatment. Adherence was assessed using the four-item Morisky, Green and Levine Medication Adherence Questionnaire (MGL). Medical records were analyzed for the number of medication changes, due to glaucoma progression.
    RESULTS:
    Adherence to topical glaucoma medication was categorized as 'high' in 41.4% (Morisky, Green and Levine (MGL). Data were analyzed for behaviors affecting adherence, history of adherence, and reasons for changed adherence. Chi-squared test demonstrated that there was no significant association noted between adherence and changes in medication regime (χ2 (2,128)=0.968, P=0.915); however, a significantly lower adherence was detected if participants had difficulties with their drop regime (χ2 (2,128)=7.24, P=0.027) or had help with drop insertion (χ2 (1,128)=9.77, P=0.008).
    CONCLUSION:
    This study revealed a higher rate of non-adherence than has previously been demonstrated in other studies. This may be attributed to the unique design of the confidential questionnaire and the independent and sympathetic questioning techniques used. Further work to develop a specific glaucoma medication adherence questionnaire would be valuable to enhance glaucoma management
    Original languageEnglish
    Pages (from-to)431-439
    Number of pages9
    JournalPatient Preference and adherence
    Volume13
    DOIs
    Publication statusPublished - 12 Aug 2019

    Bibliographical note

    © 2019 McClelland et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/
    terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

    Keywords

    • glaucoma
    • compliance
    • adherence
    • topical medication
    • questionnaire

    Fingerprint Dive into the research topics of 'Investigation of medication adherence and reasons for poor adherence in patients on long-term glaucoma treatment regimes'. Together they form a unique fingerprint.

    Cite this