Is antibiotic therapy currently the first step in the treatment of infected acute necrotic collections of the pancreas?

Savio Barreto, John A. Windsor

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

A 48-year-old lady with pre-existing type 2 diabetes mellitus presented with abdominal pain consistent with acute pancreatitis. There were two positive systemic inflammatory response syndrome (SIRS) criteria (heart rate and respiratory rate) along with an elevated serum lipase (3500IU/L), glucose (270mg/dL), and serum creatinine (2.3mg/dL). Oliguria and elevated creatinine responded to fluid resuscitation. Close to discharge, on day 14, she developed fever (up to 39°C), abdominal pain, leucocytosis (16,000cmm) and a raised C-reactive protein level (245mg/L). A Computed Tomography (CT) scan revealed moderate pleural effusions, pancreatic necrosis with gas, and a small volume (~50ml) of fluid not encapsulated or readily drainable.
Original languageEnglish
Title of host publicationHepato-Pancreato-Biliary and Transplant Surgery
Subtitle of host publicationPractical Management of Dilemmas
EditorsQ Chu, C Vollmer, G Zibari, S Orloff, M Williams, M Gimenez
Place of PublicationLos Angeles
PublisherBeaux Books Publishing
Chapter163
Pages1140-1143
Number of pages4
ISBN (Print)9780997772197
Publication statusPublished - 2018

Keywords

  • Antibiotic Therapy
  • Acute Necrotic Collections
  • Pancreas

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