Is the disease risk and penetrance in Leber hereditary optic neuropathy actually low?

David A. Mackey, Jue Sheng Ong, Stuart MacGregor, David C. Whiteman, Jamie E. Craig, M. Isabel G. Lopez Sanchez, Lisa S. Kearns, Sandra E. Staffieri, Linda Clarke, Myra B. McGuinness, Wafaa Meteoukki, Sona Samuel, Jonathan B. Ruddle, Celia Chen, Clare L. Fraser, John Harrison, Neil Howell, Alex W. Hewitt

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Agricultural and Biological Sciences

Biochemistry, Genetics and Molecular Biology