Is the disease risk and penetrance in Leber hereditary optic neuropathy actually low?

David A. Mackey, Jue Sheng Ong, Stuart MacGregor, David C. Whiteman, Jamie E. Craig, M. Isabel G. Lopez Sanchez, Lisa S. Kearns, Sandra E. Staffieri, Linda Clarke, Myra B. McGuinness, Wafaa Meteoukki, Sona Samuel, Jonathan B. Ruddle, Celia Chen, Clare L. Fraser, John Harrison, Neil Howell, Alex W. Hewitt

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Biochemistry, Genetics and Molecular Biology

Agricultural and Biological Sciences