Isolation of microorganisms for biotechnologicai application

Christopher M.M. Franco, Nicholas C. McClure

Research output: Contribution to journalReview articlepeer-review

8 Citations (Scopus)


The extent of biological diversity being revealed by molecular techniques accentuates the need to develop methods to isolate and culture the large numbers of microorganisms that remain to be studied. The discovery and characterisation of novel microorganisms will provide information useful in understanding microbial ecosystems and have the potential to lead to new products for the biotechnology industry. In this review, the use of innovative techniques and exploration of unusual ecosystems, that have begun to address the challenge of isolating the 'uncultured' members of the microbial population, are examined.

Original languageEnglish
Pages (from-to)101-110
Number of pages10
Issue number2
Publication statusPublished - 22 Jun 1998


  • Biological diversity
  • Bioprospecting
  • Cultivation
  • Ecological sources
  • Immunocapture
  • Isolation techniques
  • Microorganisms
  • Phage selection

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