Abstract
(Figure Presented) Not bad at all: A simple biological circuit composed of two integrated molecular switches was developed for the detection and amplification of a specific nucleic acid in a biological extract. The nucleic acid is recognized by a molecular beacon, then a DNA polymerase and nicking endonuclease are used to rapidly amplify the signal for sensitive detection of the nucleic acid.
| Original language | English |
|---|---|
| Pages (from-to) | 2720-2723 |
| Number of pages | 4 |
| Journal | Angewandte Chemie-International Edition |
| Volume | 49 |
| Issue number | 15 |
| DOIs | |
| Publication status | Published - 1 Apr 2010 |
Keywords
- Biosensors
- DNA detection
- DNA nanomachines
- Molecular devices
- Nanobiotechnology
Fingerprint
Dive into the research topics of 'Isothermal detection of DNA by beacon-assisted detection amplification.'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver