Strongyloides hyper-infection: a case for awareness

A. Potter, D. Stephens, B. De Keulenaer

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

In patients receiving immunosuppressive therapies, Strongyloides stercoralis can cause a life-threatening septic shock, with multi-organ failure and infestation. Strongyloides hyper-infection should be considered in any immunosuppressed patient who has been exposed to the parasite, even if it is many years since that exposure occurred. Delayed eosinophilia may be a feature and treatment with high doses of anthelmintics may be required. An interesting case of S. stercoralis hyper-infection was recently observed at the Royal Darwin Hospital in tropical, northern Australia. The patient was an 18-year-old female with lupus glomerulonephritis, who was receiving immunosuppression in the form of corticosteroids and pulse cyclophosphamide. The characteristics and intensive-care management of this case, including the use of granulocyte-colony stimulating factor and high-dose ivermectin, are described. The patient, who survived, appears to represent the first reported case of S. stercoralis hyper-infection with suspected myocarditis.

Original languageEnglish
Pages (from-to)855-860
Number of pages6
JournalAnnals of Tropical Medicine and Parasitology
Volume97
Issue number8
DOIs
Publication statusPublished - Dec 2003
Externally publishedYes

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