Karyomegalic Interstitial Nephritis:: Case Series and Review of Literature

Humaira Nasir; Nida Saleem; Fatima Anwar; Rabia Saleem; Rabia Saleem; Syed Nayer Mahmud

doi:10.12691/ajmcr-9-12-8

Karyomegalic Interstitial Nephritis: Case Series and Review of Literature

Humaira Nasir, Nida Saleem, Fatima Anwar, Rabia Saleem, Rabia Saleem, Syed Nayer Mahmud

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Abstract

Karyomegalic interstitial nephritis(KIN) is a rare cause of hereditary interstitial nephritis, described 45 years ago. Only about 50 cases have been described in English literature so far and none from Pakistan. This disease has an escalated course with a worsened outcome. There are a few potential mimickers of this disease both clinically and histologically, which might lead to a missed diagnosis and hence poor management. We have described here a series of 05 cases of KIN that were diagnosed at our institute for a better understanding of this disease entity.

Original language	English
Pages (from-to)	693-697
Number of pages	5
Journal	American Journal of Medical Case Reports
Volume	9
Issue number	12
DOIs	https://doi.org/10.12691/ajmcr-9-12-8
Publication status	Published - 2021
Externally published	Yes

Keywords

interstitial nephritis
karyomegalic interstitial nephritis
chronic kidney disease
histopathology
kidney transplantation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.12691/ajmcr-9-12-8Licence: CC BY

Published versionFinal published version, 261 KBLicence: CC BY

Cite this

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title = "Karyomegalic Interstitial Nephritis:: Case Series and Review of Literature",

abstract = "Karyomegalic interstitial nephritis(KIN) is a rare cause of hereditary interstitial nephritis, described 45 years ago. Only about 50 cases have been described in English literature so far and none from Pakistan. This disease has an escalated course with a worsened outcome. There are a few potential mimickers of this disease both clinically and histologically, which might lead to a missed diagnosis and hence poor management. We have described here a series of 05 cases of KIN that were diagnosed at our institute for a better understanding of this disease entity.",

keywords = "interstitial nephritis, karyomegalic interstitial nephritis, chronic kidney disease, histopathology, kidney transplantation",

author = "Humaira Nasir and Nida Saleem and Fatima Anwar and {Rabia Saleem} and Rabia Saleem and Mahmud, {Syed Nayer}",

year = "2021",

doi = "10.12691/ajmcr-9-12-8",

language = "English",

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pages = "693--697",

journal = "American Journal of Medical Case Reports",

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T1 - Karyomegalic Interstitial Nephritis:

T2 - Case Series and Review of Literature

AU - Nasir, Humaira

AU - Saleem, Nida

AU - Anwar, Fatima

AU - Rabia Saleem

AU - Saleem, Rabia

AU - Mahmud, Syed Nayer

PY - 2021

Y1 - 2021

N2 - Karyomegalic interstitial nephritis(KIN) is a rare cause of hereditary interstitial nephritis, described 45 years ago. Only about 50 cases have been described in English literature so far and none from Pakistan. This disease has an escalated course with a worsened outcome. There are a few potential mimickers of this disease both clinically and histologically, which might lead to a missed diagnosis and hence poor management. We have described here a series of 05 cases of KIN that were diagnosed at our institute for a better understanding of this disease entity.

AB - Karyomegalic interstitial nephritis(KIN) is a rare cause of hereditary interstitial nephritis, described 45 years ago. Only about 50 cases have been described in English literature so far and none from Pakistan. This disease has an escalated course with a worsened outcome. There are a few potential mimickers of this disease both clinically and histologically, which might lead to a missed diagnosis and hence poor management. We have described here a series of 05 cases of KIN that were diagnosed at our institute for a better understanding of this disease entity.

KW - interstitial nephritis

KW - karyomegalic interstitial nephritis

KW - chronic kidney disease

KW - histopathology

KW - kidney transplantation

U2 - 10.12691/ajmcr-9-12-8

DO - 10.12691/ajmcr-9-12-8

M3 - Article

SN - 2374-2151

VL - 9

SP - 693

EP - 697

JO - American Journal of Medical Case Reports

JF - American Journal of Medical Case Reports

IS - 12

ER -